| SP | Arrieta, J.Arrieta, Jake † >> | 30 | 2016 | R | 97 | 20 | 20 | 11 | 5 | 3.46 | .300 | 1.25 | 7.8 | 3.5 | 9.1 | 137.2 | 118 | 56 | 53 | 8 | 54 | 139 | 1 | 0 | 0 | 1 | 14 | 5 | 4 | 3.02 |
| SP | Harvey, M.Harvey, Matt >> | 27 | 2016 | R | 24 | 20 | 20 | 6 | 7 | 3.84 | .283 | 1.15 | 8.6 | 1.8 | 7.3 | 119.2 | 114 | 51 | 51 | 10 | 24 | 96 | 0 | 0 | 0 | 0 | 9 | 4 | 2 | 3.18 |
| CL | Flynn, B.Flynn, Brian † >> | 26 | 2016 | L | 85 | 37 | 0 | 4 | 4 | 2.14 | .280 | 1.14 | 6.0 | 4.3 | 8.6 | 42.0 | 28 | 11 | 10 | 2 | 20 | 40 | 0 | 19 | 1 | 0 | 0 | 1 | 6 | 3.21 |
| RP | LeBlanc, W.LeBlanc, Wade >> | 32 | 2016 | L | 66 | 49 | 0 | 2 | 3 | 4.11 | .303 | 1.28 | 9.7 | 1.9 | 6.8 | 100.2 | 108 | 50 | 46 | 10 | 21 | 76 | 0 | 1 | 4 | 0 | 0 | 2 | 0 | 3.47 |
| RP | Rodney, F.Rodney, Fernando >> | 39 | 2016 | R | 51 | 59 | 0 | 2 | 3 | 3.12 | .295 | 1.20 | 7.1 | 3.9 | 9.3 | 60.2 | 47 | 21 | 21 | 3 | 26 | 62 | 0 | 0 | 3 | 0 | 0 | 3 | 4 | 3.03 |
| RP | Moylan, P.Moylan, Peter >> | 38 | 2016 | R | 44 | 42 | 0 | 1 | 1 | 4.04 | .310 | 1.29 | 9.0 | 2.8 | 6.9 | 35.2 | 35 | 16 | 16 | 8 | 11 | 27 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 5.54 |
| RP | Wilson, J.Wilson, Justin >> | 28 | 2016 | L | 41 | 48 | 0 | 1 | 1 | 3.57 | .316 | 1.36 | 7.5 | 4.9 | 10.3 | 35.1 | 29 | 14 | 14 | 5 | 19 | 40 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.29 |
| RP | Axford, J.Axford, John >> | 33 | 2016 | R | 30 | 24 | 0 | 0 | 2 | 5.55 | .330 | 1.48 | 10.5 | 3.0 | 9.0 | 24.1 | 28 | 15 | 15 | 3 | 8 | 24 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.63 |