| SP | Keuchel, D.Keuchel, Dallas >> | 28 | 2016 | L | 62 | 21 | 21 | 7 | 11 | 5.40 | .348 | 1.58 | 10.9 | 3.4 | 8.2 | 126.2 | 153 | 82 | 76 | 10 | 47 | 115 | 0 | 0 | 0 | 0 | 8 | 3 | 7 | 3.40 |
| SP | Wisler, M.Wisler, Matt >> | 23 | 2016 | R | 47 | 21 | 21 | 3 | 11 | 4.54 | .330 | 1.43 | 10.1 | 2.8 | 8.7 | 115.0 | 129 | 63 | 58 | 15 | 36 | 111 | 0 | 0 | 0 | 0 | 12 | 5 | 3 | 3.83 |
| SP | Dickey, R.Dickey, R.A. # >> | 42 | 2016 | R | 46 | 20 | 20 | 7 | 4 | 4.19 | .300 | 1.25 | 9.2 | 2.1 | 8.6 | 120.1 | 123 | 58 | 56 | 10 | 28 | 115 | 0 | 0 | 0 | 0 | 10 | 4 | 3 | 2.97 |
| RP | Gregerson, L.Gregerson, Luke >> | 32 | 2016 | R | 95 | 46 | 0 | 3 | 4 | 1.91 | .306 | 1.28 | 8.6 | 3.0 | 10.9 | 42.1 | 40 | 11 | 9 | 1 | 14 | 51 | 0 | 4 | 3 | 0 | 0 | 2 | 1 | 2.02 |
| RP | Bedrosian, C.Bedrosian, Cam >> | 24 | 2016 | R | 88 | 36 | 0 | 5 | 1 | 2.34 | .257 | 0.98 | 7.1 | 1.9 | 9.8 | 34.2 | 27 | 9 | 9 | 4 | 7 | 37 | 0 | 5 | 0 | 0 | 0 | 2 | 2 | 3.15 |
| RP | Rodriguez, F.Rodriguez, Fernando >> | 32 | 2016 | R | 78 | 20 | 0 | 1 | 1 | 5.40 | .350 | 1.52 | 9.9 | 4.3 | 8.1 | 21.2 | 23 | 13 | 13 | 1 | 10 | 19 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 3.52 |
| RP | Rusin, C.Rusin, Chris # >> | 29 | 2016 | L | 50 | 41 | 0 | 3 | 3 | 6.49 | .344 | 1.53 | 10.4 | 3.5 | 8.2 | 59.2 | 68 | 46 | 43 | 4 | 23 | 54 | 0 | 6 | 1 | 0 | 0 | 3 | 2 | 3.37 |
| RP | Rogers, T.Rogers, Taylor >> | 25 | 2016 | L | 47 | 35 | 0 | 0 | 1 | 1.87 | .289 | 1.16 | 7.9 | 2.7 | 9.3 | 33.2 | 29 | 7 | 7 | 1 | 10 | 34 | 0 | 2 | 0 | 0 | 0 | 2 | 2 | 2.42 |