| SP | Darvish, Y.Darvish, Yu >> | 29 | 2016 | R | 95 | 22 | 22 | 7 | 8 | 2.97 | .256 | 1.00 | 6.7 | 2.4 | 11.4 | 142.1 | 105 | 49 | 47 | 13 | 38 | 180 | 0 | 0 | 0 | 0 | 15 | 4 | 6 | 2.54 |
| SP | Wright, S.Wright, Steven # >> | 31 | 2016 | R | 74 | 21 | 21 | 10 | 8 | 3.02 | .286 | 1.15 | 7.2 | 3.1 | 7.3 | 143.0 | 115 | 60 | 48 | 10 | 49 | 116 | 3 | 0 | 0 | 0 | 14 | 8 | 11 | 3.48 |
| SP | Gonzalez, M.Gonzalez, Miguel >> | 32 | 2016 | R | 66 | 21 | 21 | 5 | 10 | 4.14 | .306 | 1.28 | 8.6 | 3.0 | 7.4 | 121.2 | 116 | 67 | 56 | 12 | 40 | 99 | 0 | 0 | 0 | 0 | 11 | 5 | 5 | 3.77 |
| RP | Watson, T.Watson, Tony >> | 31 | 2016 | L | 83 | 68 | 0 | 2 | 0 | 2.53 | .230 | 0.88 | 6.3 | 1.6 | 9.6 | 57.0 | 40 | 17 | 16 | 5 | 10 | 61 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 2.58 |
| RP | Siegrist, K.Siegrist, Kevin >> | 26 | 2016 | L | 88 | 39 | 0 | 1 | 2 | 3.81 | .286 | 1.20 | 8.0 | 2.9 | 10.3 | 28.1 | 25 | 14 | 12 | 4 | 9 | 32 | 0 | 7 | 0 | 0 | 0 | 0 | 1 | 3.54 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 34 | 2016 | R | 79 | 67 | 0 | 6 | 0 | 2.89 | .249 | 0.91 | 5.1 | 3.2 | 6.7 | 62.1 | 35 | 23 | 20 | 7 | 22 | 46 | 0 | 3 | 1 | 0 | 0 | 5 | 4 | 4.29 |
| RP | Withrow, C.Withrow, Chris >> | 27 | 2016 | R | 65 | 57 | 0 | 2 | 3 | 2.65 | .298 | 1.24 | 7.8 | 3.4 | 7.4 | 51.0 | 44 | 18 | 15 | 3 | 19 | 42 | 0 | 8 | 1 | 0 | 0 | 2 | 0 | 3.35 |
| RP | Ellington, B.Ellington, Brian >> | 25 | 2016 | R | 61 | 25 | 0 | 1 | 1 | 2.31 | .278 | 1.16 | 6.3 | 4.3 | 8.6 | 23.1 | 16 | 7 | 6 | 1 | 11 | 22 | 0 | 1 | 1 | 0 | 0 | 0 | 4 | 3.09 |
| RP | Ramirez, J.Ramirez, Jose >> | 26 | 2016 | R | 54 | 22 | 0 | 0 | 2 | 3.68 | .371 | 1.73 | 9.8 | 5.7 | 11.5 | 22.0 | 24 | 10 | 9 | 2 | 14 | 28 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 3.68 |
| SP | Perez, M.Perez, Martin >> | 25 | 2016 | L | 36 | 25 | 0 | 6 | 4 | 4.40 | .319 | 1.39 | 8.6 | 4.0 | 7.2 | 61.1 | 58 | 31 | 30 | 5 | 27 | 49 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.84 |