| SP | Feliz, N.Feliz, Neftali >> | 24 | 2012 | R | 88 | 25 | 25 | 8 | 7 | 3.95 | .328 | 1.41 | 8.4 | 4.4 | 8.2 | 134.1 | 125 | 66 | 59 | 12 | 65 | 122 | 0 | 0 | 0 | 0 | 6 | 7 | 0 | 3.96 |
| SP | Dempster, R.Dempster, Ryan >> | 35 | 2012 | R | 86 | 25 | 25 | 6 | 14 | 5.79 | .331 | 1.44 | 10.0 | 3.0 | 7.4 | 150.2 | 167 | 102 | 97 | 21 | 50 | 123 | 2 | 0 | 0 | 1 | 9 | 7 | 0 | 4.32 |
| SP | McDonald, J.McDonald, James >> | 28 | 2012 | R | 79 | 24 | 24 | 8 | 10 | 4.30 | .329 | 1.44 | 9.3 | 3.7 | 8.0 | 138.0 | 142 | 71 | 66 | 21 | 57 | 122 | 0 | 0 | 0 | 0 | 14 | 4 | 0 | 4.54 |
| SP | Cahill, T.Cahill, Trevor >> | 24 | 2012 | R | 65 | 22 | 22 | 8 | 10 | 5.08 | .329 | 1.45 | 9.3 | 3.7 | 8.1 | 131.0 | 136 | 77 | 74 | 16 | 54 | 118 | 1 | 0 | 0 | 1 | 8 | 3 | 5 | 4.09 |
| SP | Lincecum, T.Lincecum, Tim >> | 28 | 2012 | R | 46 | 18 | 18 | 6 | 8 | 5.70 | .359 | 1.62 | 9.8 | 4.8 | 9.1 | 90.0 | 98 | 59 | 57 | 9 | 48 | 91 | 0 | 0 | 0 | 0 | 7 | 5 | 6 | 4.04 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 99 | 73 | 0 | 2 | 1 | 1.83 | .238 | 0.91 | 4.5 | 3.8 | 11.7 | 88.2 | 44 | 18 | 18 | 2 | 37 | 114 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 2.03 |
| RP | O'Day, D.O'Day, Darren >> | 30 | 2012 | R | 94 | 64 | 0 | 2 | 4 | 3.26 | .248 | 0.99 | 6.5 | 2.4 | 9.3 | 80.0 | 58 | 29 | 29 | 9 | 21 | 83 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 3.18 |
| RP | Atchison, S.Atchison, Scott >> | 36 | 2012 | R | 81 | 51 | 0 | 8 | 3 | 3.10 | .281 | 1.16 | 8.5 | 1.9 | 7.9 | 58.0 | 55 | 20 | 20 | 4 | 12 | 51 | 0 | 7 | 2 | 0 | 0 | 1 | 1 | 2.81 |
| RP | Albers, M.Albers, Matt >> | 29 | 2012 | R | 79 | 29 | 0 | 4 | 1 | 1.97 | .262 | 1.06 | 7.0 | 2.5 | 8.7 | 32.0 | 25 | 7 | 7 | 2 | 9 | 31 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 2.72 |
| RP | Melancon, M.Melancon, Mark >> | 27 | 2012 | R | 47 | 24 | 0 | 1 | 0 | 3.90 | .268 | 1.10 | 6.9 | 3.0 | 6.6 | 30.0 | 23 | 13 | 13 | 6 | 10 | 22 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 5.13 |
| RP | Luetge, L.Luetge, Lucas >> | 25 | 2012 | L | 31 | 83 | 0 | 0 | 1 | 3.04 | .298 | 1.27 | 6.1 | 5.4 | 9.5 | 77.0 | 52 | 28 | 26 | 4 | 46 | 81 | 0 | 3 | 3 | 0 | 0 | 0 | 7 | 3.36 |
| SP | Mendoza, L.Mendoza, Luis >> | 29 | 2012 | R | 30 | 11 | 0 | 0 | 2 | 9.00 | .400 | 2.00 | 13.1 | 4.9 | 6.5 | 11.0 | 16 | 11 | 11 | 2 | 6 | 8 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 5.55 |