| SP | Eickhoff, J.Eickhoff, Jerad >> | 25 | 2016 | R | 82 | 21 | 21 | 9 | 6 | 3.88 | .299 | 1.24 | 9.0 | 2.2 | 7.4 | 127.2 | 127 | 59 | 55 | 11 | 31 | 104 | 0 | 0 | 0 | 0 | 10 | 5 | 4 | 3.34 |
| SP | DeSclafani, A.DeSclafani, Anthony >> | 26 | 2016 | R | 73 | 19 | 19 | 9 | 8 | 5.73 | .348 | 1.54 | 10.6 | 3.4 | 8.2 | 103.2 | 121 | 66 | 66 | 17 | 39 | 94 | 0 | 0 | 0 | 0 | 7 | 6 | 6 | 4.63 |
| SP | Gausman, K.Gausman, Kevin >> | 25 | 2016 | R | 64 | 19 | 18 | 5 | 10 | 4.39 | .299 | 1.28 | 9.2 | 2.4 | 7.8 | 108.2 | 110 | 59 | 53 | 17 | 29 | 93 | 0 | 0 | 0 | 0 | 9 | 0 | 2 | 4.13 |
| SP | Lincecum, T.Lincecum, Tim >> | 32 | 2016 | R | 4 | 14 | 14 | 0 | 11 | 7.79 | .383 | 1.85 | 12.8 | 3.8 | 7.8 | 52.0 | 74 | 45 | 45 | 9 | 22 | 45 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.85 |
| RP | Melancon, M.Melancon, Mark >> | 31 | 2016 | R | 91 | 52 | 0 | 4 | 2 | 4.00 | .299 | 1.26 | 8.6 | 2.8 | 8.0 | 72.0 | 69 | 34 | 32 | 7 | 22 | 64 | 0 | 3 | 2 | 0 | 0 | 1 | 4 | 3.44 |
| RP | Feliz, N.Feliz, Neftali >> | 28 | 2016 | R | 84 | 52 | 0 | 3 | 3 | 2.63 | .257 | 1.00 | 5.8 | 3.2 | 10.6 | 68.1 | 44 | 22 | 20 | 4 | 24 | 80 | 0 | 8 | 3 | 0 | 0 | 3 | 4 | 2.60 |
| RP | O'Day, D.O'Day, Darren >> | 34 | 2016 | R | 75 | 42 | 0 | 1 | 3 | 4.45 | .268 | 1.10 | 6.8 | 3.2 | 12.0 | 54.2 | 41 | 28 | 27 | 6 | 19 | 72 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.83 |
| RP | Cahill, T.Cahill, Trevor >> | 28 | 2016 | R | 66 | 40 | 0 | 2 | 2 | 4.41 | .301 | 1.25 | 6.5 | 4.8 | 8.3 | 51.0 | 37 | 25 | 25 | 6 | 27 | 47 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 4.39 |
| RP | Wittgren, N.Wittgren, Nick >> | 25 | 2016 | R | 58 | 32 | 0 | 3 | 0 | 2.70 | .291 | 1.23 | 8.5 | 2.7 | 10.4 | 33.1 | 31 | 10 | 10 | 2 | 10 | 38 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.39 |
| RP | Goeddel, E.Goeddel, Erik >> | 27 | 2016 | R | 49 | 22 | 0 | 0 | 1 | 2.96 | .330 | 1.48 | 9.8 | 3.8 | 13.5 | 24.1 | 26 | 10 | 8 | 3 | 10 | 36 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.88 |
| RP | Hendriks, L.Hendriks, Liam >> | 27 | 2016 | R | 45 | 24 | 0 | 1 | 0 | 3.30 | .274 | 1.07 | 7.2 | 2.4 | 10.5 | 30.0 | 24 | 12 | 11 | 4 | 8 | 35 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 3.40 |