| SP | Maholm, P.Maholm, Paul # >> | 30 | 2012 | L | 73 | 25 | 25 | 12 | 9 | 3.79 | .326 | 1.41 | 10.6 | 2.2 | 6.8 | 149.2 | 175 | 64 | 63 | 13 | 36 | 112 | 1 | 0 | 0 | 0 | 15 | 6 | 1 | 3.48 |
| SP | Bailey, H.Bailey, Homer >> | 26 | 2012 | R | 65 | 24 | 24 | 11 | 7 | 4.38 | .326 | 1.43 | 10.4 | 2.5 | 6.4 | 150.0 | 173 | 79 | 73 | 18 | 42 | 106 | 0 | 0 | 0 | 0 | 15 | 3 | 4 | 4.05 |
| SP | Blanton, J.Blanton, Joe # >> | 32 | 2012 | R | 57 | 23 | 23 | 9 | 10 | 4.63 | .308 | 1.30 | 10.0 | 1.7 | 9.2 | 138.0 | 154 | 77 | 71 | 9 | 26 | 141 | 1 | 0 | 0 | 1 | 12 | 4 | 0 | 2.46 |
| SP | Buchholz, C.Buchholz, Clay # >> | 28 | 2012 | R | 52 | 23 | 23 | 10 | 9 | 4.80 | .348 | 1.59 | 11.0 | 3.3 | 6.7 | 146.1 | 178 | 81 | 78 | 12 | 54 | 108 | 1 | 0 | 0 | 0 | 10 | 2 | 4 | 3.74 |
| CL | Benoit, J.Benoit, Joaquin † >> | 35 | 2012 | R | 79 | 49 | 0 | 1 | 4 | 2.91 | .329 | 1.40 | 9.2 | 3.5 | 9.8 | 46.1 | 47 | 16 | 15 | 5 | 18 | 50 | 0 | 30 | 1 | 0 | 0 | 3 | 1 | 3.61 |
| RP | Rapada, C.Rapada, Clay >> | 31 | 2012 | L | 77 | 66 | 0 | 2 | 1 | 3.48 | .238 | 0.90 | 6.1 | 2.0 | 9.3 | 62.0 | 42 | 25 | 24 | 9 | 14 | 64 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.60 |
| RP | Hughes, J.Hughes, Jared >> | 26 | 2012 | R | 64 | 73 | 0 | 1 | 0 | 3.59 | .310 | 1.29 | 8.6 | 3.1 | 7.3 | 72.2 | 69 | 30 | 29 | 8 | 25 | 58 | 0 | 1 | 2 | 0 | 0 | 4 | 4 | 4.04 |