| SP | Hellickson, J.Hellickson, Jeremy † >> | 29 | 2016 | R | 84 | 20 | 20 | 10 | 4 | 2.26 | .232 | 0.90 | 6.0 | 2.1 | 7.9 | 139.1 | 92 | 38 | 35 | 15 | 33 | 122 | 2 | 0 | 0 | 2 | 15 | 1 | 2 | 3.38 |
| SP | Finnegan, B.Finnegan, Brandon >> | 23 | 2016 | L | 64 | 18 | 18 | 6 | 6 | 4.09 | .333 | 1.46 | 9.1 | 4.1 | 6.0 | 99.0 | 100 | 52 | 45 | 13 | 45 | 66 | 0 | 0 | 0 | 0 | 7 | 3 | 3 | 4.83 |
| SP | Tillman, C.Tillman, Chris >> | 28 | 2016 | R | 72 | 18 | 18 | 6 | 7 | 3.93 | .316 | 1.36 | 8.5 | 3.8 | 7.9 | 107.2 | 101 | 51 | 47 | 15 | 45 | 94 | 0 | 0 | 0 | 0 | 8 | 3 | 4 | 4.41 |
| SP | Jimenez, U.Jimenez, Ubaldo # >> | 32 | 2016 | R | 29 | 17 | 15 | 3 | 7 | 4.84 | .333 | 1.48 | 9.5 | 3.8 | 7.0 | 80.0 | 84 | 47 | 43 | 9 | 34 | 62 | 0 | 0 | 0 | 0 | 4 | 2 | 3 | 4.26 |
| RP | Iglesias, R.Iglesias, Raisel >> | 26 | 2016 | R | 80 | 58 | 0 | 2 | 4 | 2.72 | .274 | 1.13 | 7.2 | 3.0 | 10.3 | 76.0 | 61 | 25 | 23 | 8 | 25 | 87 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 3.07 |
| RP | Hochevar, L.Hochevar, Luke >> | 33 | 2016 | R | 82 | 48 | 0 | 3 | 3 | 2.91 | .245 | 0.97 | 7.0 | 1.8 | 10.4 | 46.1 | 36 | 17 | 15 | 4 | 9 | 53 | 0 | 3 | 1 | 0 | 0 | 0 | 3 | 2.41 |
| RP | Kintzler, B.Kintzler, Brandon >> | 31 | 2016 | R | 41 | 25 | 0 | 1 | 1 | 4.79 | .287 | 1.21 | 9.5 | 1.8 | 5.9 | 20.2 | 21 | 11 | 11 | 3 | 4 | 13 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.25 |
| RP | Cingrani, T.Cingrani, Tony >> | 26 | 2016 | L | 39 | 36 | 0 | 2 | 1 | 2.73 | .301 | 1.22 | 6.9 | 4.2 | 8.0 | 26.1 | 20 | 8 | 8 | 1 | 12 | 23 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 3.35 |
| RP | Hatcher, C.Hatcher, Chris >> | 31 | 2016 | R | 28 | 17 | 0 | 0 | 2 | 3.00 | .276 | 1.14 | 7.7 | 2.6 | 9.0 | 21.0 | 18 | 7 | 7 | 3 | 6 | 21 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.71 |