| SP | Sabathia, C.Sabathia, CC >> | 32 | 2012 | L | 91 | 27 | 27 | 9 | 12 | 3.52 | .285 | 1.19 | 8.7 | 2.0 | 7.9 | 199.2 | 193 | 93 | 78 | 19 | 45 | 174 | 8 | 0 | 0 | 2 | 16 | 1 | 3 | 3.19 |
| SP | Estrada, M.Estrada, Marco # >> | 29 | 2012 | R | 89 | 25 | 25 | 6 | 13 | 4.14 | .314 | 1.34 | 9.8 | 2.3 | 10.8 | 121.2 | 132 | 64 | 56 | 12 | 31 | 145 | 0 | 0 | 0 | 0 | 1 | 4 | 5 | 2.76 |
| SP | Halladay, R.Halladay, Roy >> | 35 | 2012 | R | 69 | 25 | 25 | 6 | 12 | 4.82 | .337 | 1.49 | 10.2 | 3.2 | 7.1 | 153.0 | 174 | 92 | 82 | 20 | 54 | 120 | 2 | 0 | 0 | 0 | 12 | 5 | 1 | 4.29 |
| SP | Guthrie, J.Guthrie, Jeremy >> | 33 | 2012 | R | 26 | 31 | 15 | 4 | 14 | 6.14 | .357 | 1.63 | 11.6 | 3.1 | 7.2 | 126.0 | 163 | 98 | 86 | 22 | 43 | 101 | 0 | 0 | 1 | 0 | 2 | 4 | 2 | 4.79 |
| RP | Rodriguez, F.Rodriguez, Fernando >> | 28 | 2012 | R | 34 | 49 | 0 | 2 | 3 | 2.60 | .297 | 1.27 | 6.4 | 5.1 | 9.7 | 55.1 | 39 | 19 | 16 | 1 | 31 | 59 | 0 | 6 | 1 | 0 | 0 | 0 | 2 | 2.78 |
| RP | Padilla, V.Padilla, Vicente >> | 35 | 2012 | R | 20 | 38 | 0 | 3 | 3 | 4.70 | .307 | 1.33 | 7.8 | 4.3 | 7.6 | 38.1 | 33 | 21 | 20 | 4 | 18 | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.11 |