| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 99 | 21 | 21 | 8 | 8 | 3.37 | .303 | 1.27 | 9.1 | 2.4 | 7.9 | 125.2 | 127 | 58 | 47 | 10 | 33 | 110 | 0 | 0 | 0 | 0 | 12 | 4 | 6 | 3.17 |
| SP | Martinez, C.Martinez, Carlos >> | 25 | 2016 | R | 84 | 20 | 20 | 3 | 8 | 3.05 | .296 | 1.24 | 7.8 | 3.3 | 7.8 | 127.0 | 110 | 55 | 43 | 10 | 47 | 110 | 1 | 0 | 0 | 1 | 12 | 3 | 3 | 3.47 |
| SP | Estrada, M.Estrada, Marco >> | 33 | 2016 | R | 94 | 20 | 20 | 4 | 9 | 4.91 | .309 | 1.30 | 7.8 | 3.9 | 8.2 | 121.0 | 105 | 71 | 66 | 18 | 52 | 110 | 0 | 0 | 0 | 0 | 7 | 5 | 0 | 4.53 |
| SP | Sabathia, C.Sabathia, CC >> | 36 | 2016 | L | 59 | 18 | 18 | 2 | 13 | 5.50 | .355 | 1.59 | 10.5 | 3.9 | 7.5 | 93.1 | 108 | 71 | 57 | 16 | 40 | 77 | 0 | 0 | 0 | 0 | 6 | 6 | 1 | 5.06 |
| CL | Achter, A.Achter, A.J. >> | 27 | 2016 | R | 14 | 20 | 0 | 0 | 3 | 7.46 | .361 | 1.70 | 10.8 | 4.7 | 6.1 | 25.1 | 30 | 21 | 21 | 6 | 13 | 17 | 0 | 6 | 4 | 0 | 0 | 0 | 0 | 6.32 |
| SU | Caminero, A.Caminero, Arquimedes >> | 29 | 2016 | R | 10 | 21 | 0 | 0 | 2 | 1.82 | .245 | 0.97 | 6.8 | 2.3 | 8.3 | 24.2 | 18 | 5 | 5 | 1 | 6 | 22 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 2.46 |
| RP | Ramos, E.Ramos, Edubray >> | 23 | 2016 | R | 69 | 52 | 0 | 0 | 0 | 2.83 | .300 | 1.22 | 7.6 | 3.4 | 9.5 | 76.1 | 64 | 31 | 24 | 9 | 29 | 80 | 0 | 1 | 1 | 0 | 0 | 5 | 0 | 3.78 |
| RP | Wang, C.Wang, Chien-Ming >> | 36 | 2016 | R | 17 | 42 | 0 | 3 | 4 | 4.85 | .361 | 1.63 | 11.9 | 2.8 | 8.1 | 52.0 | 69 | 30 | 28 | 11 | 16 | 47 | 0 | 4 | 4 | 0 | 0 | 3 | 0 | 5.04 |
| RP | Gonzalez, S.Gonzalez, Severino >> | 23 | 2016 | R | 35 | 45 | 0 | 4 | 3 | 3.31 | .291 | 1.20 | 9.2 | 1.7 | 7.3 | 54.1 | 55 | 25 | 20 | 6 | 10 | 44 | 0 | 5 | 1 | 0 | 0 | 2 | 0 | 3.48 |
| RP | Burgos, E.Burgos, Enrique >> | 26 | 2016 | R | 36 | 42 | 0 | 4 | 5 | 6.33 | .380 | 1.76 | 11.3 | 4.7 | 10.3 | 48.1 | 60 | 42 | 34 | 6 | 25 | 55 | 0 | 2 | 1 | 0 | 0 | 4 | 6 | 4.15 |