| SP | Bieber, S.Bieber, Shane † >> | 25 | 2020 | R | 99 | 43 | 43 | 18 | 9 | 2.25 | .243 | 0.94 | 5.5 | 2.9 | 10.7 | 292.1 | 180 | 76 | 73 | 22 | 94 | 346 | 4 | 0 | 0 | 3 | 33 | 7 | 10 | 2.65 |
| SP | Peralta, F.Peralta, Freddy >> | 25 | 2021 | R | 94 | 43 | 43 | 17 | 12 | 2.98 | .287 | 1.16 | 6.8 | 3.6 | 9.4 | 242.0 | 184 | 83 | 80 | 19 | 96 | 253 | 0 | 0 | 0 | 0 | 23 | 12 | 3 | 3.27 |
| SP | Woodruff, B.Woodruff, Brandon >> | 28 | 2021 | R | 90 | 42 | 42 | 10 | 17 | 4.01 | .312 | 1.33 | 8.2 | 3.8 | 9.9 | 240.0 | 219 | 112 | 107 | 27 | 101 | 265 | 0 | 0 | 0 | 0 | 23 | 6 | 5 | 3.59 |
| SP | Burnes, C.Burnes, Corbin † >> | 26 | 2021 | R | 90 | 41 | 41 | 18 | 10 | 2.86 | .287 | 1.17 | 7.8 | 2.8 | 9.2 | 252.0 | 217 | 90 | 80 | 24 | 79 | 258 | 0 | 0 | 0 | 0 | 28 | 9 | 1 | 3.24 |
| SP | Houser, A.Houser, Adrian >> | 28 | 2021 | R | 55 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| CL | Hader, J.Hader, Josh † >> | 27 | 2021 | L | 100 | 48 | 0 | 0 | 2 | 1.61 | .283 | 1.14 | 6.8 | 3.7 | 11.7 | 44.2 | 33 | 10 | 8 | 2 | 18 | 57 | 0 | 41 | 5 | 0 | 0 | 2 | 3 | 2.36 |
| SU | Richards, T.Richards, Trevor >> | 28 | 2021 | R | 91 | 36 | 0 | 1 | 0 | 3.11 | .271 | 1.09 | 7.8 | 2.2 | 11.7 | 37.2 | 32 | 13 | 13 | 4 | 9 | 48 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 2.62 |
| RP | Boxberger, B.Boxberger, Brad >> | 33 | 2021 | R | 84 | 87 | 0 | 5 | 9 | 2.99 | .286 | 1.16 | 5.8 | 4.7 | 9.0 | 108.1 | 70 | 39 | 36 | 7 | 56 | 108 | 0 | 0 | 2 | 0 | 0 | 4 | 9 | 3.51 |
| RP | Cousins, J.Cousins, Jake >> | 26 | 2021 | R | 82 | 70 | 0 | 7 | 4 | 1.94 | .260 | 1.03 | 5.6 | 3.7 | 8.9 | 83.2 | 52 | 19 | 18 | 5 | 34 | 82 | 0 | 1 | 3 | 0 | 0 | 2 | 6 | 3.11 |
| RP | Williams, D.Williams, Devin >> | 26 | 2021 | R | 75 | 46 | 0 | 7 | 2 | 1.62 | .292 | 1.24 | 7.7 | 3.4 | 11.2 | 50.0 | 43 | 11 | 9 | 3 | 19 | 62 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 2.44 |
| RP | Rasmussen, D.Rasmussen, Drew >> | 25 | 2021 | R | 76 | 23 | 0 | 4 | 4 | 2.03 | .261 | 1.06 | 7.0 | 2.7 | 7.0 | 44.1 | 34 | 10 | 10 | 2 | 13 | 34 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 2.93 |
| RP | Strickland, H.Strickland, Hunter >> | 32 | 2021 | R | 67 | 18 | 0 | 0 | 1 | 3.44 | .286 | 1.20 | 8.5 | 2.5 | 12.5 | 18.1 | 17 | 8 | 7 | 2 | 5 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.50 |
| SP | Lauer, E.Lauer, Eric # >> | 26 | 2021 | L | 71 | 20 | 0 | 3 | 3 | 3.84 | .274 | 1.10 | 6.8 | 3.1 | 9.0 | 82.0 | 62 | 43 | 35 | 11 | 28 | 82 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 3.88 |
| RP | Feyereisen, J.Feyereisen, J.P. >> | 28 | 2021 | R | 68 | 23 | 0 | 1 | 0 | 4.18 | .276 | 1.14 | 6.1 | 4.2 | 8.7 | 28.0 | 19 | 13 | 13 | 1 | 13 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.93 |