| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 92 | 30 | 30 | 6 | 20 | 4.09 | .297 | 1.24 | 9.3 | 1.9 | 9.9 | 211.1 | 217 | 99 | 96 | 34 | 44 | 233 | 7 | 0 | 0 | 2 | 16 | 7 | 6 | 3.61 |
| SP | Buehrle, M.Buehrle, Mark # >> | 22 | 2001 | L | 66 | 29 | 29 | 10 | 12 | 5.47 | .343 | 1.53 | 10.3 | 3.5 | 6.3 | 158.0 | 181 | 105 | 96 | 27 | 61 | 110 | 0 | 0 | 0 | 0 | 14 | 6 | 3 | 5.10 |
| SP | Nolasco, R.Nolasco, Ricky # >> | 26 | 2008 | R | 56 | 28 | 28 | 12 | 9 | 4.70 | .327 | 1.42 | 10.2 | 2.7 | 6.2 | 176.1 | 199 | 97 | 92 | 29 | 52 | 121 | 1 | 0 | 0 | 0 | 12 | 6 | 4 | 4.76 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 70 | 72 | 0 | 5 | 0 | 4.12 | .326 | 1.40 | 8.6 | 4.1 | 6.4 | 91.2 | 87 | 42 | 42 | 15 | 41 | 65 | 0 | 6 | 3 | 0 | 0 | 5 | 3 | 5.23 |
| RP | Vizcaino, L.Vizcaino, Luis >> | 28 | 2002 | R | 46 | 57 | 0 | 6 | 2 | 5.26 | .354 | 1.57 | 10.0 | 4.2 | 7.1 | 65.0 | 72 | 39 | 38 | 6 | 30 | 51 | 0 | 5 | 2 | 0 | 0 | 5 | 1 | 4.25 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 35 | 47 | 0 | 5 | 3 | 5.28 | .331 | 1.45 | 7.9 | 5.1 | 10.6 | 58.0 | 51 | 34 | 34 | 10 | 33 | 68 | 0 | 4 | 2 | 0 | 0 | 2 | 4 | 4.71 |
| RP | Seanez, R.Seanez, Rudy >> | 37 | 2005 | R | 23 | 43 | 0 | 1 | 1 | 5.50 | .329 | 1.41 | 9.0 | 3.8 | 10.2 | 52.1 | 52 | 34 | 32 | 8 | 22 | 59 | 0 | 4 | 0 | 0 | 0 | 3 | 3 | 4.17 |
| SP | Appier, K.Appier, Kevin >> | 34 | 2001 | R | 37 | 2 | 0 | 0 | 0 | 10.80 | .412 | 2.10 | 18.0 | 3.0 | 6.0 | 3.1 | 6 | 4 | 4 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.00 |
| SP | Person, R.Person, Robert >> | 32 | 2001 | R | 25 | 25 | 0 | 2 | 5 | 5.40 | .356 | 1.63 | 9.4 | 5.5 | 5.3 | 41.2 | 43 | 25 | 25 | 7 | 25 | 24 | 0 | 6 | 2 | 0 | 0 | 1 | 5 | 5.95 |