| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 14 | 14 | 4 | 7 | 4.26 | .284 | 1.16 | 7.8 | 2.7 | 9.1 | 95.0 | 82 | 47 | 45 | 18 | 28 | 96 | 4 | 0 | 0 | 0 | 8 | 3 | 2 | 4.42 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 95 | 13 | 13 | 4 | 6 | 4.14 | .298 | 1.26 | 8.7 | 2.7 | 9.8 | 87.0 | 84 | 43 | 40 | 14 | 26 | 95 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 3.84 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 93 | 13 | 13 | 4 | 8 | 7.21 | .360 | 1.65 | 11.6 | 3.3 | 6.1 | 68.2 | 88 | 57 | 55 | 17 | 25 | 46 | 0 | 0 | 0 | 0 | 5 | 3 | 0 | 6.13 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 73 | 14 | 13 | 2 | 10 | 7.33 | .377 | 1.79 | 11.4 | 4.7 | 5.7 | 81.0 | 103 | 67 | 66 | 13 | 42 | 51 | 2 | 0 | 0 | 0 | 3 | 2 | 0 | 5.46 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 36 | 0 | 1 | 1 | 2.30 | .266 | 1.09 | 6.3 | 3.4 | 10.9 | 47.0 | 33 | 13 | 12 | 5 | 18 | 57 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 3.11 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 31 | 0 | 3 | 3 | 2.61 | .266 | 1.06 | 6.8 | 2.9 | 11.0 | 41.1 | 31 | 12 | 12 | 5 | 13 | 50 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.17 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 25 | 0 | 1 | 0 | 3.29 | .364 | 1.68 | 8.3 | 7.0 | 6.0 | 27.1 | 25 | 10 | 10 | 3 | 21 | 18 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 5.56 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 15 | 0 | 0 | 1 | 11.37 | .493 | 2.84 | 22.5 | 4.5 | 9.8 | 12.2 | 30 | 18 | 16 | 3 | 6 | 13 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.83 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 55 | 14 | 0 | 0 | 1 | 3.72 | .310 | 1.34 | 8.5 | 3.8 | 8.5 | 19.1 | 18 | 10 | 8 | 2 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.74 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 51 | 7 | 0 | 0 | 0 | 5.40 | .250 | 1.00 | 3.6 | 5.4 | 16.2 | 5.0 | 2 | 3 | 3 | 1 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.80 |