| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 33 | 33 | 14 | 16 | 4.34 | .305 | 1.28 | 9.6 | 2.0 | 8.9 | 240.1 | 255 | 118 | 116 | 41 | 53 | 237 | 6 | 0 | 0 | 1 | 20 | 8 | 3 | 4.01 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 32 | 32 | 17 | 12 | 3.83 | .284 | 1.17 | 8.0 | 2.6 | 9.2 | 211.1 | 188 | 93 | 90 | 36 | 60 | 215 | 1 | 0 | 0 | 0 | 21 | 4 | 3 | 4.09 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 63 | 32 | 32 | 9 | 13 | 4.49 | .316 | 1.38 | 8.9 | 3.5 | 7.0 | 206.1 | 204 | 106 | 103 | 31 | 80 | 161 | 1 | 0 | 0 | 1 | 18 | 2 | 2 | 4.59 |
| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 59 | 30 | 30 | 10 | 13 | 4.60 | .333 | 1.48 | 9.0 | 4.3 | 8.9 | 209.1 | 209 | 109 | 107 | 24 | 100 | 207 | 2 | 0 | 0 | 1 | 13 | 5 | 5 | 4.02 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 73 | 0 | 5 | 4 | 3.64 | .299 | 1.21 | 7.7 | 3.2 | 9.9 | 89.0 | 76 | 39 | 36 | 8 | 32 | 98 | 0 | 13 | 3 | 0 | 0 | 6 | 0 | 3.25 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 72 | 53 | 0 | 3 | 5 | 4.14 | .290 | 1.16 | 7.4 | 3.1 | 9.8 | 58.2 | 48 | 27 | 27 | 9 | 20 | 63 | 0 | 10 | 4 | 0 | 0 | 4 | 2 | 4.09 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 62 | 25 | 0 | 0 | 0 | 3.06 | .265 | 1.08 | 7.9 | 2.0 | 11.3 | 32.1 | 28 | 11 | 11 | 3 | 7 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.38 |