| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 13 | 13 | 0 | 8 | 5.14 | .360 | 1.65 | 10.8 | 4.1 | 9.0 | 75.1 | 90 | 46 | 43 | 20 | 34 | 75 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 5.95 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 13 | 13 | 2 | 7 | 7.43 | .363 | 1.70 | 11.9 | 3.4 | 7.8 | 69.0 | 91 | 59 | 57 | 21 | 26 | 60 | 0 | 0 | 0 | 0 | 3 | 1 | 5 | 6.39 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 13 | 13 | 2 | 7 | 6.01 | .333 | 1.49 | 10.4 | 3.1 | 6.7 | 85.1 | 98 | 58 | 57 | 13 | 29 | 63 | 2 | 0 | 0 | 0 | 4 | 1 | 1 | 4.56 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 13 | 13 | 3 | 9 | 5.47 | .329 | 1.43 | 9.3 | 3.6 | 5.0 | 82.1 | 85 | 53 | 50 | 15 | 33 | 46 | 1 | 0 | 0 | 0 | 5 | 3 | 1 | 5.57 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 36 | 0 | 3 | 1 | 2.29 | .260 | 0.98 | 5.7 | 3.1 | 9.2 | 55.0 | 35 | 15 | 14 | 4 | 19 | 56 | 0 | 4 | 2 | 0 | 0 | 4 | 2 | 3.16 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 49 | 19 | 0 | 0 | 1 | 6.20 | .322 | 1.43 | 9.9 | 3.2 | 9.9 | 20.1 | 22 | 15 | 14 | 5 | 7 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.10 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 2 | 0 | 1 | 0 | 6.00 | .280 | 1.17 | 7.5 | 3.0 | 16.5 | 6.0 | 5 | 4 | 4 | 2 | 2 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.67 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 56 | 17 | 1 | 2 | 1 | 3.60 | .286 | 1.20 | 7.2 | 3.6 | 4.9 | 35.0 | 28 | 15 | 14 | 6 | 14 | 19 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.34 |