| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 27 | 27 | 9 | 13 | 4.92 | .333 | 1.47 | 10.4 | 3.0 | 5.4 | 173.2 | 199 | 99 | 95 | 32 | 57 | 104 | 3 | 0 | 0 | 1 | 12 | 4 | 3 | 5.26 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 26 | 26 | 9 | 15 | 5.15 | .319 | 1.37 | 9.6 | 2.8 | 5.5 | 171.1 | 182 | 103 | 98 | 26 | 53 | 105 | 8 | 0 | 0 | 2 | 10 | 6 | 4 | 4.78 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 26 | 26 | 8 | 14 | 4.73 | .319 | 1.40 | 9.6 | 3.1 | 5.0 | 182.2 | 194 | 99 | 96 | 27 | 62 | 101 | 5 | 0 | 0 | 1 | 11 | 1 | 5 | 4.86 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 26 | 26 | 13 | 8 | 4.48 | .314 | 1.36 | 10.3 | 2.0 | 8.5 | 170.2 | 195 | 92 | 85 | 25 | 37 | 160 | 2 | 0 | 0 | 1 | 15 | 2 | 6 | 3.72 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 61 | 24 | 24 | 2 | 11 | 7.14 | .389 | 1.88 | 10.6 | 6.4 | 8.0 | 104.2 | 123 | 88 | 83 | 22 | 74 | 92 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 6.20 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 71 | 0 | 2 | 4 | 3.35 | .309 | 1.33 | 6.6 | 5.4 | 11.5 | 83.1 | 61 | 32 | 31 | 8 | 50 | 106 | 0 | 10 | 1 | 0 | 0 | 1 | 4 | 3.54 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 41 | 0 | 2 | 1 | 4.74 | .358 | 1.66 | 8.9 | 6.0 | 5.1 | 76.0 | 75 | 44 | 40 | 9 | 51 | 43 | 0 | 7 | 1 | 0 | 0 | 1 | 0 | 5.46 |
| RP | Abernathy, T.Abernathy, Ted >> | 34 | 1967 | R | 49 | 39 | 0 | 2 | 2 | 2.34 | .245 | 0.97 | 5.7 | 3.2 | 6.3 | 57.2 | 36 | 16 | 15 | 4 | 20 | 40 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.56 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 50 | 5 | 0 | 0 | 1 | 13.50 | .429 | 2.25 | 21.6 | 0.0 | 7.2 | 5.1 | 12 | 8 | 8 | 4 | 0 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 11.80 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 25 | 1 | 2 | 1 | 5.43 | .323 | 1.43 | 9.2 | 3.7 | 9.7 | 53.0 | 54 | 32 | 32 | 5 | 22 | 57 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.32 |