| SP | Kershaw, C.Kershaw, Clayton # >> | 28 | 2016 | L | 99 | 33 | 33 | 11 | 17 | 4.52 | .289 | 1.18 | 9.0 | 1.7 | 8.6 | 240.2 | 241 | 132 | 121 | 35 | 44 | 229 | 7 | 0 | 0 | 1 | 14 | 8 | 7 | 3.64 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 32 | 32 | 7 | 16 | 5.02 | .336 | 1.50 | 9.2 | 4.4 | 5.5 | 211.2 | 215 | 124 | 118 | 16 | 102 | 129 | 2 | 0 | 0 | 1 | 15 | 4 | 4 | 4.27 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 88 | 0 | 7 | 3 | 2.83 | .245 | 0.97 | 6.6 | 2.1 | 9.1 | 130.1 | 95 | 42 | 41 | 11 | 31 | 131 | 0 | 11 | 3 | 0 | 0 | 1 | 2 | 2.82 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 74 | 0 | 2 | 6 | 4.48 | .339 | 1.53 | 7.4 | 6.4 | 10.6 | 88.1 | 72 | 46 | 44 | 9 | 63 | 104 | 0 | 6 | 1 | 0 | 0 | 1 | 6 | 4.15 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 50 | 0 | 1 | 2 | 3.83 | .305 | 1.30 | 8.2 | 3.5 | 9.3 | 56.1 | 51 | 26 | 24 | 8 | 22 | 58 | 0 | 6 | 2 | 0 | 0 | 1 | 3 | 4.02 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 6 | 0 | 1 | 0 | 12.00 | .486 | 2.83 | 10.5 | 15.0 | 4.5 | 6.0 | 7 | 8 | 8 | 1 | 10 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.17 |