| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 33 | 33 | 8 | 18 | 5.54 | .322 | 1.40 | 9.1 | 3.5 | 8.7 | 178.2 | 180 | 119 | 110 | 21 | 70 | 172 | 0 | 0 | 0 | 0 | 12 | 4 | 3 | 3.85 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 32 | 32 | 13 | 10 | 4.90 | .317 | 1.37 | 9.0 | 3.3 | 8.1 | 202.0 | 202 | 118 | 110 | 24 | 74 | 181 | 6 | 0 | 0 | 2 | 13 | 5 | 2 | 3.93 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 32 | 32 | 5 | 16 | 7.00 | .364 | 1.69 | 11.3 | 4.1 | 4.9 | 164.2 | 205 | 143 | 128 | 37 | 74 | 89 | 2 | 0 | 0 | 1 | 7 | 4 | 1 | 6.27 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 32 | 32 | 8 | 14 | 5.83 | .365 | 1.71 | 9.3 | 6.1 | 6.8 | 160.2 | 166 | 119 | 104 | 23 | 108 | 120 | 0 | 0 | 0 | 0 | 9 | 3 | 3 | 5.45 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 31 | 31 | 10 | 15 | 5.37 | .353 | 1.60 | 10.7 | 3.7 | 4.8 | 192.2 | 229 | 134 | 115 | 22 | 79 | 102 | 8 | 0 | 0 | 2 | 12 | 7 | 3 | 4.77 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 78 | 0 | 5 | 6 | 3.74 | .289 | 1.20 | 7.5 | 3.3 | 10.5 | 101.0 | 84 | 49 | 42 | 8 | 37 | 118 | 0 | 6 | 6 | 0 | 0 | 2 | 8 | 2.85 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 74 | 0 | 2 | 4 | 5.08 | .354 | 1.60 | 8.8 | 5.6 | 9.2 | 83.1 | 81 | 54 | 47 | 15 | 52 | 85 | 0 | 2 | 4 | 0 | 0 | 4 | 1 | 5.33 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 62 | 0 | 5 | 6 | 4.17 | .294 | 1.24 | 7.2 | 4.0 | 10.2 | 77.2 | 62 | 40 | 36 | 6 | 34 | 87 | 0 | 4 | 4 | 0 | 0 | 1 | 3 | 3.12 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 48 | 0 | 2 | 2 | 4.72 | .350 | 1.59 | 8.2 | 6.3 | 11.7 | 47.2 | 43 | 25 | 25 | 5 | 33 | 61 | 0 | 5 | 1 | 0 | 0 | 1 | 4 | 3.96 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 26 | 0 | 2 | 0 | 2.77 | .297 | 1.27 | 5.2 | 6.2 | 5.5 | 26.0 | 15 | 9 | 8 | 2 | 18 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.85 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 28 | 0 | 0 | 0 | 5.34 | .377 | 1.78 | 10.0 | 6.4 | 7.1 | 28.2 | 31 | 18 | 17 | 4 | 20 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 5.54 |