| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 13 | 13 | 6 | 4 | 3.19 | .279 | 1.15 | 7.0 | 3.4 | 9.2 | 93.0 | 72 | 36 | 33 | 9 | 35 | 95 | 2 | 0 | 0 | 0 | 9 | 1 | 1 | 3.38 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 83 | 13 | 13 | 3 | 8 | 5.25 | .292 | 1.23 | 7.6 | 3.4 | 8.3 | 84.0 | 71 | 51 | 49 | 17 | 32 | 77 | 1 | 0 | 0 | 1 | 7 | 1 | 1 | 4.98 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 13 | 13 | 3 | 6 | 5.63 | .347 | 1.56 | 10.1 | 4.1 | 4.0 | 84.2 | 94 | 54 | 53 | 10 | 38 | 37 | 1 | 0 | 0 | 0 | 5 | 3 | 3 | 5.13 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 43 | 12 | 12 | 5 | 5 | 5.83 | .358 | 1.66 | 9.7 | 5.3 | 8.0 | 66.1 | 71 | 44 | 43 | 8 | 39 | 59 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 4.61 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 36 | 0 | 2 | 1 | 1.88 | .230 | 0.90 | 6.8 | 1.3 | 7.5 | 48.0 | 36 | 11 | 10 | 2 | 7 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.31 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 15 | 0 | 1 | 2 | 2.81 | .273 | 1.13 | 5.1 | 5.1 | 10.7 | 16.0 | 9 | 5 | 5 | 1 | 9 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.13 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 10 | 0 | 1 | 0 | 3.46 | .291 | 1.23 | 9.0 | 2.1 | 9.0 | 13.0 | 13 | 5 | 5 | 1 | 3 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.69 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 70 | 14 | 0 | 2 | 0 | 1.62 | .254 | 1.02 | 3.9 | 5.6 | 8.4 | 16.2 | 7 | 3 | 3 | 1 | 10 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.81 |