| SP | Johnson, W.Johnson, Walter $ >> | 26 | 1913 | R | 95 | 34 | 34 | 16 | 13 | 3.92 | .292 | 1.21 | 8.8 | 2.1 | 5.0 | 234.0 | 230 | 113 | 102 | 22 | 54 | 130 | 5 | 0 | 0 | 0 | 22 | 5 | 5 | 3.87 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 33 | 33 | 16 | 10 | 4.92 | .314 | 1.34 | 8.9 | 3.2 | 9.0 | 205.0 | 202 | 120 | 112 | 23 | 73 | 206 | 4 | 0 | 0 | 1 | 15 | 7 | 3 | 3.62 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 31 | 30 | 7 | 13 | 7.01 | .346 | 1.58 | 10.6 | 3.7 | 5.3 | 145.0 | 170 | 124 | 113 | 29 | 59 | 85 | 0 | 0 | 0 | 0 | 6 | 1 | 3 | 5.67 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 66 | 0 | 2 | 7 | 4.24 | .300 | 1.23 | 8.4 | 2.7 | 8.4 | 63.2 | 59 | 32 | 30 | 14 | 19 | 59 | 0 | 39 | 6 | 0 | 0 | 4 | 0 | 5.11 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 74 | 0 | 7 | 1 | 3.93 | .341 | 1.54 | 9.4 | 4.5 | 8.2 | 66.1 | 69 | 31 | 29 | 7 | 33 | 60 | 0 | 3 | 4 | 0 | 0 | 1 | 1 | 4.11 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 53 | 0 | 5 | 6 | 4.80 | .318 | 1.36 | 9.3 | 3.0 | 7.2 | 54.1 | 56 | 31 | 29 | 8 | 18 | 43 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 4.44 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 34 | 0 | 0 | 1 | 4.50 | .325 | 1.44 | 7.4 | 5.6 | 9.3 | 34.0 | 28 | 17 | 17 | 4 | 21 | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.32 |