| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 27 | 27 | 10 | 8 | 3.72 | .290 | 1.20 | 9.1 | 1.6 | 8.4 | 184.0 | 187 | 78 | 76 | 21 | 33 | 171 | 1 | 0 | 0 | 0 | 17 | 5 | 1 | 3.24 |
| SP | Gibson, B.Gibson, Bob † >> | 33 | 1968 | R | 93 | 27 | 27 | 13 | 8 | 2.80 | .260 | 1.05 | 6.9 | 2.5 | 4.3 | 199.0 | 153 | 68 | 62 | 19 | 55 | 96 | 11 | 0 | 0 | 3 | 18 | 2 | 0 | 4.14 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 26 | 26 | 9 | 12 | 4.42 | .289 | 1.21 | 9.2 | 1.8 | 8.5 | 154.2 | 157 | 82 | 76 | 22 | 30 | 145 | 5 | 0 | 0 | 2 | 14 | 2 | 2 | 3.60 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 26 | 26 | 6 | 10 | 5.93 | .367 | 1.71 | 11.2 | 4.2 | 4.1 | 147.1 | 183 | 103 | 97 | 18 | 69 | 67 | 4 | 0 | 0 | 0 | 9 | 4 | 1 | 5.17 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 56 | 0 | 3 | 1 | 3.49 | .294 | 1.23 | 6.1 | 5.0 | 8.4 | 59.1 | 40 | 24 | 23 | 4 | 33 | 55 | 0 | 7 | 0 | 0 | 0 | 1 | 2 | 3.75 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 37 | 0 | 3 | 0 | 2.50 | .256 | 1.03 | 6.7 | 2.8 | 11.3 | 39.2 | 29 | 12 | 11 | 3 | 12 | 49 | 0 | 3 | 0 | 0 | 0 | 0 | 4 | 2.41 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 29 | 0 | 1 | 1 | 2.54 | .220 | 0.82 | 6.5 | 0.9 | 6.7 | 39.0 | 28 | 11 | 11 | 4 | 4 | 29 | 0 | 6 | 0 | 0 | 0 | 1 | 0 | 3.23 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 79 | 0 | 8 | 4 | 3.27 | .297 | 1.24 | 8.2 | 3.0 | 7.1 | 71.2 | 65 | 30 | 26 | 10 | 24 | 56 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 4.35 |