| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 6 | 6 | 3 | 2 | 2.95 | .261 | 1.03 | 6.9 | 2.5 | 9.9 | 39.2 | 30 | 13 | 13 | 3 | 11 | 43 | 1 | 0 | 0 | 0 | 5 | 1 | 0 | 2.72 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 6 | 6 | 3 | 3 | 4.74 | .278 | 1.16 | 8.1 | 2.4 | 7.6 | 38.0 | 34 | 20 | 20 | 5 | 10 | 32 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 3.82 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 6 | 6 | 4 | 1 | 5.71 | .362 | 1.70 | 10.9 | 4.8 | 5.8 | 34.2 | 41 | 22 | 22 | 7 | 18 | 22 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 5.97 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 23 | 0 | 1 | 0 | 4.05 | .286 | 1.20 | 7.6 | 3.5 | 9.0 | 13.1 | 11 | 6 | 6 | 2 | 5 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.15 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 22 | 0 | 0 | 0 | 5.56 | .306 | 1.32 | 5.7 | 6.5 | 8.2 | 11.1 | 7 | 7 | 7 | 0 | 8 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.36 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 19 | 0 | 0 | 0 | 5.91 | .319 | 1.31 | 10.8 | 1.8 | 6.3 | 10.2 | 12 | 7 | 7 | 1 | 2 | 7 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 3.80 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 11 | 0 | 0 | 0 | 1.29 | .364 | 1.71 | 7.7 | 7.7 | 6.4 | 7.0 | 6 | 1 | 1 | 0 | 6 | 5 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.14 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 11 | 0 | 0 | 2 | 2.19 | .288 | 1.22 | 7.5 | 3.8 | 3.0 | 12.1 | 10 | 7 | 3 | 2 | 5 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.75 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 5 | 0 | 0 | 0 | 3.60 | .286 | 1.20 | 9.0 | 1.8 | 7.2 | 5.0 | 5 | 2 | 2 | 0 | 1 | 4 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 7 | 0 | 1 | 0 | 4.15 | .301 | 1.29 | 8.1 | 3.9 | 3.9 | 21.2 | 19 | 10 | 10 | 3 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 5.29 |