| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 7 | 7 | 1 | 4 | 4.25 | .359 | 1.68 | 12.2 | 3.0 | 8.6 | 42.1 | 57 | 28 | 20 | 3 | 14 | 40 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 3.02 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 6 | 6 | 0 | 2 | 3.63 | .276 | 1.14 | 8.6 | 1.8 | 9.0 | 44.2 | 42 | 19 | 18 | 7 | 9 | 44 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 3.68 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 6 | 6 | 3 | 2 | 1.72 | .203 | 0.73 | 5.0 | 1.6 | 4.0 | 52.1 | 29 | 10 | 10 | 2 | 9 | 23 | 3 | 0 | 0 | 1 | 5 | 2 | 0 | 3.25 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 6 | 6 | 2 | 0 | 4.03 | .306 | 1.30 | 8.8 | 3.1 | 3.9 | 44.2 | 43 | 24 | 20 | 7 | 15 | 19 | 1 | 0 | 0 | 0 | 3 | 1 | 0 | 5.30 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 6 | 6 | 1 | 4 | 5.06 | .337 | 1.47 | 9.5 | 3.9 | 3.9 | 37.1 | 39 | 24 | 21 | 8 | 16 | 16 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 6.41 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 16 | 0 | 3 | 3 | 3.54 | .315 | 1.38 | 9.0 | 3.6 | 9.5 | 20.1 | 20 | 9 | 8 | 3 | 8 | 21 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 4.05 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 11 | 0 | 2 | 0 | 0.00 | .244 | 0.97 | 4.1 | 4.9 | 9.8 | 11.1 | 5 | 0 | 0 | 0 | 6 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.45 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 7 | 0 | 0 | 0 | 0.00 | .242 | 0.96 | 4.5 | 4.5 | 12.4 | 8.1 | 4 | 0 | 0 | 0 | 4 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.75 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 4 | 0 | 1 | 2 | 5.40 | .412 | 2.10 | 18.0 | 3.0 | 15.0 | 3.1 | 6 | 2 | 2 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.67 |