| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 28 | 28 | 9 | 14 | 4.58 | .299 | 1.26 | 8.0 | 3.3 | 8.2 | 206.1 | 184 | 112 | 105 | 28 | 75 | 187 | 8 | 0 | 0 | 0 | 16 | 5 | 4 | 4.12 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 27 | 27 | 12 | 5 | 3.18 | .281 | 1.14 | 6.9 | 3.3 | 4.7 | 187.0 | 144 | 70 | 66 | 13 | 69 | 98 | 3 | 0 | 0 | 1 | 17 | 6 | 1 | 4.06 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 27 | 27 | 12 | 10 | 3.97 | .315 | 1.33 | 9.8 | 2.2 | 4.6 | 186.0 | 202 | 92 | 82 | 16 | 45 | 96 | 2 | 0 | 0 | 1 | 17 | 10 | 5 | 3.97 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 26 | 26 | 13 | 11 | 4.41 | .307 | 1.27 | 8.5 | 3.0 | 4.1 | 187.2 | 177 | 102 | 92 | 23 | 62 | 85 | 5 | 0 | 0 | 1 | 12 | 10 | 2 | 4.84 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 42 | 0 | 0 | 1 | 1.98 | .255 | 0.95 | 4.4 | 4.2 | 9.0 | 41.0 | 20 | 11 | 9 | 2 | 19 | 41 | 0 | 36 | 3 | 0 | 0 | 3 | 0 | 3.24 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 48 | 0 | 6 | 3 | 3.04 | .260 | 1.01 | 6.8 | 2.3 | 8.3 | 50.1 | 38 | 17 | 17 | 7 | 13 | 46 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 3.88 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 32 | 0 | 1 | 3 | 5.35 | .336 | 1.46 | 11.2 | 2.2 | 7.9 | 33.2 | 41 | 22 | 20 | 7 | 8 | 29 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.91 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 21 | 0 | 1 | 1 | 4.35 | .374 | 1.79 | 10.4 | 6.3 | 9.5 | 20.2 | 23 | 12 | 10 | 0 | 14 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.00 |