| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 7 | 7 | 0 | 5 | 4.73 | .259 | 1.03 | 7.0 | 2.4 | 10.0 | 45.2 | 35 | 24 | 24 | 6 | 12 | 50 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 3.38 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 7 | 7 | 3 | 4 | 4.18 | .276 | 1.14 | 7.7 | 2.6 | 5.6 | 56.0 | 48 | 26 | 26 | 4 | 16 | 35 | 5 | 0 | 0 | 0 | 3 | 0 | 0 | 3.54 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 6 | 6 | 2 | 1 | 4.27 | .305 | 1.29 | 10.0 | 1.8 | 6.7 | 46.1 | 51 | 22 | 22 | 8 | 9 | 34 | 1 | 0 | 0 | 1 | 2 | 1 | 1 | 4.43 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 16 | 0 | 0 | 1 | 3.05 | .333 | 1.45 | 9.5 | 4.1 | 8.1 | 20.2 | 21 | 7 | 7 | 1 | 9 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 3.35 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 10 | 0 | 1 | 1 | 10.57 | .465 | 2.61 | 10.3 | 15.4 | 7.7 | 7.2 | 8 | 9 | 9 | 3 | 12 | 6 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 12.00 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 7 | 0 | 0 | 1 | 8.10 | .355 | 1.65 | 15.0 | 1.5 | 3.0 | 6.2 | 10 | 6 | 6 | 2 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.17 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 6 | 0 | 0 | 0 | 1.17 | .042 | 0.00 | 0.0 | 0.0 | 9.0 | 7.2 | 0 | 1 | 1 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1.43 |