| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 34 | 34 | 12 | 15 | 3.48 | .260 | 1.05 | 6.7 | 2.7 | 9.6 | 230.1 | 171 | 90 | 89 | 26 | 70 | 245 | 1 | 0 | 0 | 1 | 24 | 2 | 0 | 3.28 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 33 | 33 | 12 | 15 | 4.41 | .310 | 1.32 | 8.8 | 3.1 | 9.0 | 218.1 | 214 | 112 | 107 | 38 | 74 | 217 | 3 | 0 | 0 | 3 | 16 | 6 | 1 | 4.38 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 32 | 32 | 10 | 20 | 5.31 | .333 | 1.46 | 10.4 | 2.8 | 4.5 | 240.2 | 276 | 148 | 142 | 28 | 75 | 120 | 11 | 0 | 0 | 0 | 10 | 9 | 2 | 4.57 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 32 | 32 | 11 | 14 | 4.96 | .314 | 1.35 | 9.9 | 2.2 | 5.5 | 243.0 | 267 | 139 | 134 | 31 | 60 | 148 | 12 | 0 | 0 | 2 | 12 | 7 | 8 | 4.27 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 86 | 0 | 7 | 4 | 3.80 | .320 | 1.39 | 8.3 | 4.3 | 8.9 | 111.1 | 102 | 48 | 47 | 13 | 53 | 110 | 0 | 5 | 5 | 0 | 0 | 2 | 5 | 4.03 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 48 | 0 | 5 | 3 | 4.71 | .344 | 1.53 | 9.0 | 5.0 | 9.0 | 49.2 | 49 | 28 | 26 | 7 | 27 | 49 | 0 | 8 | 2 | 0 | 0 | 2 | 1 | 4.63 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 30 | 0 | 2 | 2 | 3.60 | .300 | 1.26 | 10.0 | 1.3 | 6.2 | 35.0 | 39 | 14 | 14 | 4 | 5 | 24 | 0 | 4 | 1 | 0 | 0 | 1 | 2 | 3.63 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 30 | 0 | 0 | 0 | 2.87 | .260 | 0.93 | 5.8 | 2.6 | 10.2 | 31.1 | 20 | 12 | 10 | 1 | 9 | 35 | 0 | 2 | 0 | 0 | 0 | 4 | 2 | 2.42 |