| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 25 | 25 | 7 | 13 | 4.93 | .314 | 1.36 | 8.4 | 3.9 | 9.8 | 142.1 | 132 | 79 | 78 | 26 | 61 | 155 | 0 | 0 | 0 | 0 | 14 | 2 | 0 | 4.53 |
| SP | Norris, M.Norris, Mike >> | 25 | 1980 | R | 47 | 24 | 8 | 6 | 3 | 3.15 | .315 | 1.37 | 8.4 | 4.0 | 6.9 | 97.0 | 90 | 34 | 34 | 7 | 43 | 74 | 0 | 0 | 0 | 0 | 5 | 1 | 3 | 3.77 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 74 | 23 | 23 | 6 | 11 | 5.95 | .339 | 1.53 | 9.8 | 4.1 | 7.2 | 128.2 | 139 | 88 | 85 | 36 | 58 | 102 | 3 | 0 | 0 | 2 | 5 | 1 | 3 | 6.45 |
| SP | Higuera, T.Higuera, Teddy # >> | 30 | 1988 | L | 65 | 23 | 23 | 6 | 14 | 5.27 | .332 | 1.48 | 10.4 | 2.9 | 6.6 | 123.0 | 142 | 75 | 72 | 23 | 40 | 90 | 0 | 0 | 0 | 0 | 10 | 1 | 0 | 4.97 |
| CL | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 67 | 0 | 2 | 1 | 2.73 | .241 | 0.95 | 5.2 | 3.4 | 8.9 | 66.0 | 38 | 22 | 20 | 3 | 25 | 65 | 0 | 8 | 2 | 0 | 0 | 0 | 0 | 2.76 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 64 | 0 | 3 | 2 | 2.76 | .259 | 1.05 | 5.5 | 3.9 | 12.5 | 62.0 | 38 | 19 | 19 | 5 | 27 | 86 | 0 | 21 | 5 | 0 | 0 | 0 | 2 | 2.58 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 57 | 28 | 0 | 3 | 1 | 2.81 | .294 | 1.25 | 4.7 | 6.8 | 14.4 | 25.2 | 13 | 8 | 8 | 2 | 19 | 40 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.12 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 87 | 57 | 0 | 3 | 1 | 2.79 | .326 | 1.45 | 6.9 | 6.2 | 10.1 | 42.0 | 32 | 14 | 13 | 1 | 29 | 47 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 3.14 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 92 | 23 | 17 | 2 | 8 | 5.86 | .353 | 1.63 | 11.5 | 3.3 | 9.2 | 110.2 | 140 | 72 | 72 | 25 | 40 | 113 | 0 | 0 | 0 | 0 | 5 | 1 | 2 | 5.02 |