| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 25 | 25 | 13 | 8 | 2.73 | .246 | 0.95 | 6.4 | 2.2 | 9.6 | 191.0 | 135 | 59 | 58 | 24 | 47 | 204 | 8 | 0 | 0 | 0 | 17 | 5 | 0 | 3.31 |
| SP | Buehler, W.Buehler, Walker # >> | 23 | 2018 | R | 84 | 23 | 23 | 3 | 10 | 5.88 | .332 | 1.47 | 9.3 | 3.9 | 9.5 | 104.0 | 108 | 73 | 68 | 18 | 45 | 110 | 0 | 0 | 0 | 0 | 4 | 2 | 3 | 4.49 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 95 | 25 | 25 | 7 | 10 | 4.66 | .298 | 1.24 | 8.9 | 2.3 | 10.1 | 148.2 | 147 | 77 | 77 | 28 | 38 | 166 | 2 | 0 | 0 | 0 | 12 | 4 | 4 | 4.07 |
| SP | Tanana, F.Tanana, Frank # >> | 23 | 1976 | L | 73 | 25 | 22 | 8 | 9 | 5.17 | .307 | 1.31 | 9.0 | 2.9 | 6.6 | 123.2 | 123 | 73 | 71 | 17 | 39 | 90 | 4 | 0 | 0 | 0 | 10 | 2 | 0 | 4.33 |
| CL | Kimbrel, C.Kimbrel, Craig # >> | 24 | 2012 | R | 100 | 46 | 0 | 4 | 4 | 4.30 | .281 | 1.17 | 6.7 | 3.9 | 9.8 | 46.0 | 34 | 22 | 22 | 7 | 20 | 50 | 0 | 12 | 3 | 0 | 0 | 0 | 5 | 4.11 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 65 | 67 | 0 | 2 | 2 | 2.95 | .264 | 1.06 | 7.0 | 2.5 | 9.1 | 64.0 | 50 | 22 | 21 | 10 | 18 | 65 | 0 | 1 | 3 | 0 | 0 | 1 | 3 | 3.89 |
| RP | Saucier, K.Saucier, Kevin >> | 25 | 1981 | L | 54 | 61 | 0 | 4 | 2 | 1.89 | .235 | 0.82 | 3.6 | 3.8 | 5.7 | 47.2 | 19 | 12 | 10 | 2 | 20 | 30 | 0 | 0 | 0 | 0 | 0 | 5 | 2 | 3.87 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 47 | 0 | 2 | 1 | 3.74 | .316 | 1.34 | 8.6 | 3.6 | 10.3 | 43.1 | 41 | 18 | 18 | 8 | 17 | 49 | 0 | 11 | 2 | 0 | 0 | 2 | 0 | 4.47 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 45 | 62 | 0 | 2 | 0 | 3.63 | .323 | 1.43 | 7.6 | 5.5 | 9.2 | 44.2 | 37 | 18 | 18 | 6 | 27 | 45 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.57 |