| SP | Eovaldi, N.Eovaldi, Nathan >> | 35 | 2025 | R | 99 | 38 | 38 | 15 | 11 | 3.56 | .289 | 1.19 | 8.5 | 2.3 | 5.9 | 230.0 | 216 | 95 | 91 | 25 | 58 | 151 | 1 | 0 | 0 | 1 | 23 | 6 | 12 | 3.93 |
| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 91 | 36 | 36 | 14 | 11 | 3.63 | .291 | 1.22 | 8.0 | 3.0 | 8.2 | 210.2 | 187 | 86 | 85 | 21 | 69 | 192 | 0 | 0 | 0 | 0 | 20 | 4 | 7 | 3.51 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 77 | 35 | 35 | 13 | 14 | 4.31 | .318 | 1.39 | 8.2 | 4.3 | 9.4 | 210.2 | 191 | 104 | 101 | 21 | 101 | 220 | 1 | 0 | 0 | 0 | 17 | 3 | 8 | 3.69 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 100 | 97 | 0 | 12 | 6 | 2.36 | .260 | 1.03 | 5.6 | 3.6 | 7.7 | 168.0 | 105 | 44 | 44 | 11 | 68 | 143 | 0 | 11 | 4 | 0 | 0 | 4 | 0 | 3.43 |
| RP | Uehara, K.Uehara, Koji >> | 37 | 2012 | R | 97 | 92 | 0 | 6 | 2 | 2.62 | .256 | 1.02 | 6.9 | 2.3 | 9.7 | 120.1 | 92 | 37 | 35 | 11 | 31 | 129 | 0 | 10 | 6 | 0 | 0 | 1 | 1 | 2.84 |
| RP | Armstrong, S.Armstrong, Shawn >> | 34 | 2025 | R | 93 | 63 | 0 | 7 | 0 | 3.11 | .296 | 1.23 | 8.1 | 3.0 | 8.3 | 81.0 | 73 | 28 | 28 | 6 | 27 | 75 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.19 |
| RP | Leclerc, J.Leclerc, Jose >> | 24 | 2018 | R | 98 | 62 | 0 | 4 | 9 | 4.52 | .310 | 1.30 | 7.1 | 4.7 | 8.6 | 61.2 | 48 | 35 | 31 | 9 | 32 | 58 | 0 | 11 | 5 | 0 | 0 | 3 | 1 | 4.74 |
| RP | Soria, J.Soria, Joakim >> | 30 | 2014 | R | 74 | 31 | 0 | 1 | 4 | 4.70 | .276 | 1.11 | 9.9 | 0.3 | 8.7 | 30.2 | 33 | 20 | 16 | 8 | 1 | 29 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 4.73 |
| RP | Moreno, J.Moreno, Juan >> | 26 | 2001 | L | 49 | 31 | 0 | 2 | 1 | 2.62 | .348 | 1.57 | 7.4 | 6.9 | 7.9 | 34.1 | 28 | 11 | 10 | 2 | 26 | 30 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 4.38 |
| RP | Garcia, Y.Garcia, Yimi >> | 31 | 2022 | R | 46 | 1 | 0 | 0 | 0 | 0.00 | .200 | 0.75 | 9.0 | 0.0 | 9.0 | 1.1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |