| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 93 | 36 | 36 | 20 | 12 | 2.37 | .243 | 0.94 | 6.3 | 2.2 | 7.7 | 277.0 | 194 | 82 | 73 | 18 | 67 | 236 | 9 | 0 | 0 | 3 | 26 | 6 | 3 | 2.93 |
| SP | Greinke, Z.Greinke, Zack † >> | 36 | 2019 | R | 84 | 33 | 33 | 21 | 6 | 2.47 | .259 | 1.04 | 7.2 | 2.2 | 6.3 | 233.1 | 187 | 74 | 64 | 12 | 56 | 163 | 1 | 0 | 0 | 0 | 26 | 2 | 1 | 3.02 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 80 | 33 | 33 | 17 | 10 | 3.79 | .298 | 1.25 | 9.0 | 2.2 | 8.4 | 221.0 | 222 | 98 | 93 | 25 | 55 | 207 | 5 | 0 | 0 | 0 | 20 | 5 | 6 | 3.41 |
| RP | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 78 | 102 | 0 | 5 | 4 | 1.79 | .253 | 0.99 | 5.4 | 3.6 | 6.6 | 125.2 | 75 | 28 | 25 | 11 | 50 | 92 | 0 | 19 | 6 | 0 | 0 | 3 | 7 | 3.94 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 73 | 72 | 0 | 3 | 0 | 2.18 | .278 | 1.14 | 5.7 | 4.7 | 9.5 | 86.2 | 54 | 22 | 21 | 2 | 45 | 91 | 0 | 13 | 1 | 0 | 0 | 1 | 6 | 2.79 |
| RP | Ginkel, K.Ginkel, Kevin >> | 29 | 2023 | R | 66 | 39 | 0 | 4 | 5 | 4.40 | .328 | 1.42 | 9.2 | 3.6 | 8.8 | 43.0 | 44 | 22 | 21 | 6 | 17 | 42 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 4.19 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 65 | 31 | 0 | 4 | 2 | 2.60 | .288 | 1.15 | 5.8 | 4.8 | 7.1 | 34.2 | 22 | 12 | 10 | 2 | 18 | 27 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 3.94 |
| RP | Mantei, M.Mantei, Matt >> | 27 | 2000 | R | 31 | 31 | 0 | 4 | 0 | 3.65 | .327 | 1.38 | 5.1 | 7.3 | 7.8 | 37.0 | 21 | 19 | 15 | 1 | 30 | 32 | 0 | 1 | 0 | 0 | 0 | 3 | 4 | 4.30 |