| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 92 | 20 | 20 | 11 | 5 | 4.03 | .289 | 1.20 | 8.4 | 2.4 | 6.0 | 143.0 | 134 | 66 | 64 | 19 | 38 | 96 | 7 | 0 | 0 | 3 | 9 | 2 | 0 | 4.22 |
| SP | Flaherty, J.Flaherty, Jack >> | 28 | 2024 | R | 79 | 19 | 19 | 6 | 7 | 5.91 | .344 | 1.55 | 10.7 | 3.3 | 11.0 | 85.1 | 101 | 63 | 56 | 13 | 31 | 104 | 0 | 0 | 0 | 0 | 5 | 2 | 1 | 3.71 |
| SP | Skubal, T.Skubal, Tarik >> | 27 | 2024 | L | 95 | 18 | 18 | 9 | 3 | 4.38 | .313 | 1.33 | 9.3 | 2.7 | 9.5 | 111.0 | 115 | 57 | 54 | 13 | 33 | 117 | 0 | 0 | 0 | 0 | 10 | 4 | 2 | 3.41 |
| SP | Lolich, M.Lolich, Mickey # >> | 28 | 1968 | L | 70 | 18 | 18 | 7 | 4 | 3.97 | .295 | 1.24 | 9.0 | 2.1 | 7.8 | 102.0 | 102 | 46 | 45 | 11 | 24 | 88 | 1 | 0 | 0 | 0 | 11 | 2 | 2 | 3.44 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 91 | 18 | 18 | 7 | 5 | 3.78 | .299 | 1.27 | 8.4 | 3.1 | 9.3 | 104.2 | 97 | 53 | 44 | 16 | 36 | 107 | 0 | 0 | 0 | 0 | 10 | 1 | 0 | 4.01 |
| RP | Holton, T.Holton, Tyler >> | 28 | 2024 | L | 94 | 59 | 0 | 2 | 3 | 3.38 | .292 | 1.19 | 7.0 | 3.8 | 6.6 | 45.1 | 35 | 17 | 17 | 5 | 19 | 33 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 4.38 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 83 | 52 | 0 | 2 | 2 | 2.71 | .287 | 1.15 | 6.5 | 3.9 | 6.5 | 69.2 | 50 | 22 | 21 | 5 | 30 | 50 | 0 | 0 | 2 | 0 | 0 | 4 | 6 | 3.97 |
| RP | Benoit, J.Benoit, Joaquin >> | 36 | 2013 | R | 81 | 43 | 0 | 3 | 1 | 4.00 | .286 | 1.18 | 6.6 | 4.0 | 9.4 | 45.0 | 33 | 21 | 20 | 6 | 20 | 47 | 0 | 8 | 2 | 0 | 0 | 1 | 0 | 4.04 |
| RP | Miller, S.Miller, Shelby >> | 33 | 2024 | R | 74 | 41 | 0 | 2 | 1 | 3.82 | .312 | 1.33 | 6.2 | 5.9 | 9.0 | 35.1 | 24 | 15 | 15 | 5 | 23 | 35 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 4.91 |
| RP | Smyly, D.Smyly, Drew † >> | 24 | 2013 | L | 63 | 49 | 0 | 3 | 1 | 1.67 | .279 | 1.14 | 8.0 | 2.3 | 9.0 | 43.0 | 38 | 8 | 8 | 1 | 11 | 43 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 2.14 |
| SP | Sanchez, A.Sanchez, Anibal >> | 29 | 2013 | R | 56 | 10 | 0 | 2 | 2 | 4.15 | .366 | 1.73 | 12.4 | 4.5 | 12.4 | 8.2 | 11 | 4 | 4 | 1 | 4 | 11 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.38 |