| SP | Shields, J.Shields, James # >> | 26 | 2007 | R | 90 | 28 | 28 | 9 | 9 | 4.33 | .298 | 1.24 | 9.4 | 1.9 | 6.4 | 170.1 | 177 | 89 | 82 | 16 | 35 | 120 | 0 | 0 | 0 | 0 | 18 | 5 | 5 | 3.52 |
| SP | Buehrle, M.Buehrle, Mark # >> | 28 | 2007 | L | 54 | 28 | 28 | 13 | 13 | 5.16 | .321 | 1.39 | 10.7 | 1.9 | 5.9 | 158.2 | 188 | 95 | 91 | 20 | 33 | 103 | 1 | 0 | 0 | 0 | 15 | 4 | 1 | 4.04 |
| SP | Kendrick, K.Kendrick, Kyle >> | 23 | 2007 | R | 43 | 27 | 27 | 10 | 10 | 5.43 | .313 | 1.35 | 9.8 | 2.4 | 5.0 | 160.2 | 174 | 99 | 97 | 27 | 43 | 89 | 0 | 0 | 0 | 0 | 10 | 3 | 0 | 4.94 |
| SP | Weaver, J.Weaver, Jered >> | 25 | 2007 | R | 26 | 27 | 24 | 5 | 13 | 7.96 | .384 | 1.82 | 12.9 | 3.5 | 5.4 | 113.0 | 162 | 100 | 100 | 26 | 44 | 68 | 0 | 0 | 0 | 0 | 2 | 5 | 4 | 6.09 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 96 | 72 | 0 | 3 | 4 | 4.64 | .289 | 1.20 | 7.7 | 3.1 | 7.9 | 106.2 | 91 | 55 | 55 | 18 | 37 | 93 | 0 | 3 | 4 | 0 | 0 | 2 | 3 | 4.56 |
| RP | Pinto, R.Pinto, Renyel >> | 25 | 2007 | L | 46 | 71 | 0 | 5 | 4 | 3.25 | .307 | 1.29 | 6.9 | 4.8 | 7.5 | 88.2 | 67 | 34 | 32 | 2 | 47 | 73 | 0 | 11 | 1 | 0 | 0 | 4 | 4 | 3.38 |
| RP | Brown, A.Brown, Andrew >> | 26 | 2007 | R | 34 | 55 | 0 | 5 | 2 | 5.35 | .331 | 1.47 | 9.1 | 4.2 | 9.7 | 67.1 | 68 | 40 | 40 | 7 | 31 | 72 | 0 | 3 | 0 | 0 | 0 | 1 | 2 | 3.64 |
| RP | Hennessey, B.Hennessey, Brad >> | 27 | 2007 | R | 23 | 58 | 0 | 3 | 1 | 3.57 | .293 | 1.20 | 8.0 | 3.0 | 5.3 | 70.2 | 62 | 30 | 28 | 7 | 23 | 41 | 0 | 3 | 2 | 0 | 0 | 3 | 4 | 4.24 |
| SP | Pettitte, A.Pettitte, Andy >> | 35 | 2007 | L | 19 | 26 | 3 | 2 | 4 | 5.63 | .341 | 1.51 | 10.4 | 3.3 | 6.1 | 46.1 | 53 | 31 | 29 | 2 | 17 | 31 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 3.46 |