| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 36 | 36 | 21 | 4 | 2.74 | .262 | 1.04 | 6.9 | 2.5 | 8.2 | 269.0 | 205 | 88 | 82 | 19 | 76 | 244 | 12 | 0 | 0 | 4 | 26 | 5 | 4 | 3.01 |
| SP | Snell, B.Snell, Blake $$ >> | 25 | 2018 | L | 81 | 35 | 35 | 12 | 11 | 3.83 | .297 | 1.26 | 7.3 | 4.1 | 8.8 | 197.1 | 159 | 88 | 84 | 11 | 89 | 193 | 1 | 0 | 0 | 1 | 20 | 2 | 11 | 3.15 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 33 | 33 | 14 | 11 | 4.58 | .306 | 1.30 | 8.7 | 3.0 | 5.0 | 208.1 | 200 | 110 | 106 | 20 | 70 | 116 | 7 | 0 | 0 | 0 | 17 | 5 | 7 | 4.22 |
| SP | Fernandez, S.Fernandez, Sid $$ >> | 23 | 1985 | L | 49 | 33 | 33 | 12 | 10 | 4.30 | .314 | 1.37 | 7.6 | 4.7 | 7.6 | 198.2 | 168 | 97 | 95 | 18 | 104 | 168 | 1 | 0 | 0 | 0 | 18 | 1 | 4 | 4.08 |
| SP | Reulbach, E.Reulbach, Ed $ >> | 24 | 1906 | R | 60 | 34 | 31 | 15 | 7 | 3.82 | .308 | 1.32 | 7.6 | 4.4 | 4.8 | 195.2 | 164 | 91 | 83 | 15 | 95 | 105 | 0 | 0 | 0 | 0 | 19 | 2 | 7 | 4.42 |
| CL | Kimbrel, C.Kimbrel, Craig # >> | 24 | 2012 | R | 100 | 80 | 0 | 3 | 14 | 3.83 | .302 | 1.30 | 8.0 | 3.7 | 9.6 | 89.1 | 79 | 41 | 38 | 11 | 37 | 95 | 0 | 38 | 6 | 0 | 0 | 0 | 5 | 3.72 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 94 | 0 | 10 | 5 | 3.29 | .256 | 1.01 | 7.1 | 2.0 | 8.0 | 125.2 | 99 | 46 | 46 | 12 | 28 | 111 | 0 | 2 | 2 | 0 | 0 | 3 | 0 | 3.22 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 50 | 0 | 1 | 1 | 4.29 | .351 | 1.61 | 8.8 | 5.8 | 8.0 | 56.2 | 55 | 28 | 27 | 3 | 36 | 50 | 0 | 2 | 1 | 0 | 0 | 1 | 7 | 3.89 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 48 | 0 | 7 | 3 | 4.09 | .279 | 1.15 | 5.1 | 5.2 | 8.0 | 55.0 | 31 | 25 | 25 | 4 | 32 | 49 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.96 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 38 | 0 | 1 | 1 | 3.65 | .304 | 1.29 | 6.3 | 5.3 | 10.2 | 44.1 | 31 | 18 | 18 | 3 | 26 | 50 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.45 |