| SP | Scherzer, M.Scherzer, Max $ >> | 33 | 2017 | R | 95 | 38 | 38 | 13 | 15 | 3.78 | .304 | 1.29 | 7.9 | 3.7 | 8.4 | 255.0 | 223 | 111 | 107 | 31 | 105 | 237 | 0 | 0 | 0 | 0 | 24 | 6 | 12 | 4.03 |
| SP | Maddux, G.Maddux, Greg $ >> | 29 | 1995 | R | 89 | 37 | 37 | 12 | 17 | 3.82 | .289 | 1.20 | 8.2 | 2.5 | 4.9 | 276.0 | 252 | 131 | 117 | 36 | 78 | 149 | 7 | 0 | 0 | 1 | 20 | 6 | 6 | 4.53 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 31 | 31 | 8 | 11 | 5.02 | .319 | 1.38 | 9.1 | 3.3 | 8.9 | 188.1 | 191 | 113 | 105 | 24 | 68 | 186 | 1 | 0 | 0 | 0 | 13 | 6 | 7 | 3.86 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 65 | 104 | 0 | 5 | 7 | 4.80 | .290 | 1.21 | 8.2 | 2.8 | 9.5 | 75.0 | 68 | 42 | 40 | 11 | 23 | 79 | 0 | 2 | 4 | 0 | 0 | 1 | 2 | 3.76 |
| SU | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 73 | 0 | 4 | 7 | 5.24 | .314 | 1.37 | 8.1 | 4.3 | 8.2 | 77.1 | 69 | 47 | 45 | 13 | 37 | 70 | 0 | 4 | 12 | 0 | 0 | 0 | 2 | 4.82 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 62 | 0 | 3 | 4 | 2.27 | .246 | 0.96 | 6.0 | 2.7 | 7.6 | 63.1 | 42 | 17 | 16 | 4 | 19 | 53 | 0 | 35 | 3 | 0 | 0 | 1 | 0 | 3.10 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 90 | 0 | 6 | 4 | 5.71 | .330 | 1.45 | 9.5 | 3.7 | 9.5 | 75.2 | 79 | 50 | 48 | 14 | 31 | 79 | 0 | 1 | 4 | 0 | 0 | 2 | 1 | 4.64 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 12 | 0 | 3 | 1 | 3.41 | .304 | 1.31 | 8.1 | 3.7 | 5.6 | 29.0 | 26 | 14 | 11 | 3 | 12 | 18 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.34 |