| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 29 | 29 | 12 | 9 | 3.96 | .301 | 1.25 | 8.3 | 2.9 | 9.0 | 193.1 | 178 | 93 | 85 | 21 | 63 | 192 | 1 | 0 | 0 | 0 | 19 | 9 | 1 | 3.54 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 29 | 29 | 7 | 11 | 4.53 | .323 | 1.39 | 9.7 | 2.8 | 7.6 | 175.0 | 189 | 104 | 88 | 20 | 55 | 147 | 1 | 0 | 0 | 1 | 17 | 6 | 2 | 3.85 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 28 | 28 | 8 | 14 | 6.47 | .345 | 1.57 | 11.1 | 3.1 | 5.8 | 168.1 | 208 | 131 | 121 | 25 | 57 | 108 | 1 | 0 | 0 | 0 | 10 | 1 | 0 | 4.68 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 65 | 0 | 3 | 4 | 4.16 | .298 | 1.28 | 6.7 | 4.8 | 9.9 | 71.1 | 53 | 38 | 33 | 9 | 38 | 78 | 0 | 2 | 6 | 0 | 0 | 0 | 2 | 4.06 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 61 | 0 | 4 | 4 | 3.11 | .268 | 1.08 | 7.4 | 2.4 | 8.7 | 63.2 | 52 | 23 | 22 | 7 | 17 | 61 | 0 | 34 | 5 | 0 | 0 | 1 | 0 | 3.37 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 65 | 0 | 1 | 2 | 3.16 | .334 | 1.46 | 8.1 | 5.2 | 9.4 | 68.1 | 61 | 30 | 24 | 9 | 39 | 71 | 0 | 1 | 2 | 0 | 0 | 3 | 3 | 4.49 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 49 | 0 | 8 | 1 | 3.14 | .273 | 1.10 | 6.0 | 3.9 | 6.6 | 63.0 | 42 | 26 | 22 | 5 | 27 | 46 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 3.95 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 15 | 0 | 2 | 2 | 4.30 | .310 | 1.35 | 8.6 | 3.5 | 5.9 | 23.0 | 22 | 11 | 11 | 2 | 9 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.00 |