| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 29 | 29 | 12 | 12 | 3.80 | .278 | 1.13 | 7.9 | 2.3 | 7.4 | 189.2 | 166 | 83 | 80 | 19 | 49 | 156 | 1 | 0 | 0 | 0 | 17 | 4 | 2 | 3.50 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 28 | 28 | 10 | 17 | 4.70 | .308 | 1.30 | 8.4 | 3.4 | 5.3 | 191.2 | 178 | 102 | 100 | 17 | 72 | 112 | 12 | 0 | 0 | 1 | 11 | 6 | 2 | 4.21 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 28 | 28 | 11 | 12 | 5.26 | .336 | 1.49 | 10.4 | 3.1 | 4.2 | 186.2 | 214 | 118 | 109 | 31 | 64 | 86 | 7 | 0 | 0 | 1 | 10 | 6 | 1 | 5.37 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 71 | 0 | 2 | 4 | 3.42 | .272 | 1.10 | 7.8 | 2.1 | 8.5 | 100.0 | 87 | 39 | 38 | 14 | 23 | 94 | 0 | 6 | 5 | 0 | 0 | 2 | 4 | 3.69 |
| RP | Betancourt, R.Betancourt, Rafael # >> | 32 | 2007 | R | 76 | 69 | 0 | 4 | 4 | 4.96 | .273 | 1.11 | 8.6 | 1.5 | 7.5 | 90.2 | 86 | 51 | 50 | 13 | 15 | 75 | 0 | 7 | 5 | 0 | 0 | 1 | 0 | 3.74 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 53 | 0 | 1 | 5 | 2.57 | .283 | 1.16 | 7.2 | 3.2 | 8.7 | 70.0 | 56 | 26 | 20 | 7 | 25 | 68 | 0 | 6 | 0 | 0 | 0 | 2 | 1 | 3.51 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 52 | 35 | 0 | 1 | 3 | 3.54 | .282 | 1.18 | 7.9 | 2.9 | 8.6 | 40.2 | 35 | 21 | 16 | 3 | 13 | 38 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 3.05 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 3 | 0 | 0 | 1 | 9.00 | .357 | 1.67 | 15.0 | 0.0 | 3.0 | 3.0 | 5 | 3 | 3 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 6.67 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 18 | 0 | 3 | 1 | 6.91 | .369 | 1.76 | 11.3 | 4.7 | 8.0 | 27.1 | 34 | 23 | 21 | 6 | 14 | 24 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 5.67 |