| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 34 | 34 | 12 | 14 | 4.26 | .298 | 1.24 | 8.6 | 2.5 | 7.7 | 255.2 | 245 | 124 | 121 | 30 | 71 | 218 | 8 | 0 | 0 | 0 | 19 | 9 | 5 | 3.76 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 81 | 32 | 32 | 8 | 12 | 5.29 | .330 | 1.41 | 9.0 | 3.8 | 8.1 | 189.0 | 188 | 112 | 111 | 28 | 79 | 171 | 1 | 0 | 0 | 1 | 11 | 12 | 12 | 4.56 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 79 | 32 | 32 | 15 | 12 | 4.15 | .311 | 1.33 | 9.3 | 2.7 | 5.7 | 249.1 | 258 | 127 | 115 | 28 | 74 | 159 | 11 | 0 | 0 | 4 | 15 | 5 | 6 | 4.14 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 32 | 32 | 12 | 14 | 5.31 | .342 | 1.55 | 10.3 | 3.6 | 8.0 | 210.0 | 240 | 133 | 124 | 25 | 85 | 186 | 6 | 0 | 0 | 0 | 17 | 3 | 6 | 4.03 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 82 | 0 | 4 | 5 | 3.13 | .260 | 1.04 | 7.4 | 1.9 | 9.3 | 112.0 | 92 | 39 | 39 | 14 | 24 | 116 | 0 | 7 | 3 | 0 | 0 | 2 | 2 | 3.25 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 63 | 0 | 5 | 2 | 4.86 | .325 | 1.45 | 7.5 | 5.5 | 7.8 | 74.0 | 62 | 45 | 40 | 8 | 45 | 64 | 0 | 5 | 2 | 0 | 0 | 0 | 1 | 4.50 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 52 | 0 | 0 | 4 | 3.79 | .307 | 1.33 | 7.5 | 4.6 | 6.9 | 59.1 | 49 | 25 | 25 | 10 | 30 | 45 | 0 | 0 | 2 | 0 | 0 | 0 | 5 | 5.20 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 2 | 2 | 1 | 1 | 3.14 | .306 | 1.33 | 9.0 | 3.2 | 5.8 | 14.1 | 14 | 5 | 5 | 2 | 5 | 9 | 1 | 0 | 0 | 0 | 2 | 0 | 1 | 4.64 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 6 | 0 | 0 | 2 | 4.70 | .361 | 1.63 | 7.8 | 7.2 | 1.8 | 15.1 | 13 | 8 | 8 | 0 | 12 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.20 |