| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 9 | 14 | 4.48 | .319 | 1.38 | 9.1 | 3.3 | 8.7 | 221.0 | 224 | 115 | 110 | 35 | 81 | 213 | 2 | 0 | 0 | 0 | 19 | 6 | 4 | 4.31 |
| SP | Brown, M.Brown, Mordecai † >> | 32 | 1908 | R | 85 | 33 | 33 | 14 | 14 | 3.94 | .283 | 1.17 | 8.2 | 2.4 | 4.4 | 237.2 | 215 | 112 | 104 | 27 | 62 | 117 | 7 | 0 | 0 | 2 | 18 | 4 | 4 | 4.33 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 2 | 2 | 1 | 0 | 5.06 | .360 | 1.69 | 9.0 | 7.2 | 11.7 | 10.2 | 10 | 6 | 6 | 1 | 8 | 13 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.10 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 32 | 32 | 10 | 18 | 5.14 | .318 | 1.37 | 9.9 | 2.5 | 4.8 | 220.2 | 242 | 131 | 126 | 31 | 61 | 117 | 9 | 0 | 0 | 1 | 16 | 5 | 3 | 4.67 |
| SP | Newhouser, H.Newhouser, Hal >> | 25 | 1946 | L | 31 | 30 | 30 | 15 | 7 | 3.81 | .323 | 1.41 | 8.2 | 4.5 | 6.0 | 219.2 | 200 | 94 | 93 | 13 | 110 | 146 | 4 | 0 | 0 | 1 | 18 | 4 | 8 | 4.00 |
| RP | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 94 | 95 | 0 | 11 | 2 | 3.47 | .295 | 1.25 | 6.7 | 4.6 | 9.1 | 98.2 | 73 | 40 | 38 | 8 | 50 | 99 | 0 | 12 | 1 | 0 | 0 | 1 | 4 | 3.60 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 58 | 0 | 2 | 2 | 2.80 | .253 | 0.99 | 6.7 | 2.2 | 7.4 | 74.0 | 55 | 23 | 23 | 6 | 18 | 61 | 0 | 7 | 0 | 0 | 0 | 2 | 0 | 3.22 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 36 | 0 | 1 | 2 | 3.25 | .261 | 1.04 | 6.3 | 3.1 | 7.4 | 44.1 | 31 | 18 | 16 | 1 | 15 | 36 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.75 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 31 | 0 | 6 | 1 | 3.74 | .308 | 1.31 | 8.5 | 3.5 | 7.4 | 33.2 | 31 | 14 | 14 | 4 | 13 | 27 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.21 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 1 | 0 | 0 | 0 | 9.00 | .625 | 4.00 | 27.0 | 9.0 | 0.0 | 1.0 | 3 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 9.00 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 1 | 0 | 0 | 1 | 0.00 | .286 | 1.20 | 18.0 | 0.0 | 9.0 | 1.2 | 2 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 48 | 0 | 1 | 3 | 3.32 | .298 | 1.24 | 7.3 | 4.0 | 8.7 | 59.2 | 48 | 23 | 22 | 7 | 26 | 57 | 0 | 16 | 5 | 0 | 0 | 2 | 1 | 4.03 |