| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 33 | 33 | 12 | 14 | 3.96 | .310 | 1.30 | 8.0 | 3.8 | 8.6 | 204.1 | 181 | 97 | 90 | 27 | 85 | 195 | 0 | 0 | 0 | 0 | 14 | 9 | 6 | 4.19 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 30 | 30 | 10 | 10 | 5.26 | .331 | 1.47 | 10.1 | 3.2 | 4.8 | 159.0 | 178 | 101 | 93 | 27 | 56 | 84 | 0 | 0 | 0 | 0 | 8 | 2 | 3 | 5.25 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 73 | 32 | 32 | 11 | 14 | 4.34 | .306 | 1.32 | 9.4 | 2.5 | 4.8 | 255.1 | 267 | 132 | 123 | 24 | 70 | 137 | 11 | 0 | 0 | 1 | 13 | 1 | 1 | 3.98 |
| RP | Eckersley, D.Eckersley, Dennis # >> | 36 | 1990 | R | 88 | 79 | 0 | 5 | 8 | 4.30 | .311 | 1.34 | 10.4 | 1.7 | 7.7 | 98.1 | 113 | 51 | 47 | 5 | 19 | 84 | 0 | 8 | 6 | 0 | 0 | 1 | 0 | 2.56 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 67 | 0 | 1 | 3 | 3.25 | .292 | 1.22 | 7.6 | 3.4 | 7.9 | 72.0 | 61 | 26 | 26 | 10 | 27 | 63 | 0 | 10 | 2 | 0 | 0 | 1 | 0 | 4.22 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 42 | 0 | 1 | 3 | 5.07 | .379 | 1.79 | 8.8 | 7.5 | 7.3 | 49.2 | 48 | 29 | 28 | 3 | 41 | 40 | 0 | 5 | 1 | 0 | 0 | 2 | 1 | 4.80 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 6 | 4 | 2 | 2 | 2.86 | .303 | 1.27 | 9.0 | 2.6 | 4.8 | 28.1 | 28 | 11 | 9 | 2 | 8 | 15 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 3.82 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 20 | 0 | 1 | 1 | 7.01 | .379 | 1.83 | 9.0 | 7.9 | 9.0 | 25.2 | 25 | 20 | 20 | 4 | 22 | 25 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.72 |