| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 21 | 21 | 9 | 6 | 3.47 | .283 | 1.15 | 7.5 | 2.9 | 8.4 | 142.2 | 119 | 56 | 55 | 20 | 45 | 132 | 1 | 0 | 0 | 1 | 14 | 5 | 0 | 4.03 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 78 | 20 | 20 | 9 | 9 | 3.50 | .267 | 1.10 | 7.7 | 2.2 | 5.7 | 157.0 | 134 | 68 | 61 | 14 | 38 | 99 | 9 | 0 | 0 | 2 | 12 | 0 | 3 | 3.62 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 20 | 20 | 8 | 7 | 4.33 | .317 | 1.37 | 8.8 | 3.6 | 5.2 | 126.2 | 123 | 61 | 61 | 7 | 50 | 73 | 1 | 0 | 0 | 1 | 11 | 3 | 1 | 3.83 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 19 | 19 | 2 | 14 | 9.03 | .389 | 1.87 | 13.5 | 3.5 | 4.9 | 93.2 | 139 | 100 | 94 | 24 | 36 | 51 | 1 | 0 | 0 | 1 | 5 | 4 | 3 | 6.55 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 54 | 0 | 3 | 4 | 3.58 | .282 | 1.15 | 7.2 | 3.2 | 8.0 | 70.1 | 56 | 28 | 28 | 8 | 25 | 62 | 0 | 4 | 3 | 0 | 0 | 2 | 0 | 3.87 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 32 | 0 | 0 | 0 | 2.09 | .237 | 0.93 | 5.7 | 2.7 | 7.7 | 43.0 | 27 | 11 | 10 | 0 | 13 | 37 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.19 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 26 | 0 | 1 | 1 | 4.97 | .313 | 1.37 | 8.1 | 4.3 | 8.8 | 38.0 | 34 | 21 | 21 | 6 | 18 | 37 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 4.53 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 8 | 0 | 1 | 1 | 4.86 | .342 | 1.56 | 8.4 | 6.2 | 9.0 | 16.2 | 15 | 9 | 9 | 3 | 11 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.50 |