| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 35 | 35 | 18 | 6 | 3.03 | .258 | 1.02 | 6.9 | 2.2 | 9.5 | 219.2 | 169 | 81 | 74 | 21 | 54 | 230 | 1 | 0 | 0 | 0 | 27 | 6 | 0 | 2.97 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 33 | 33 | 9 | 13 | 4.59 | .303 | 1.29 | 8.5 | 3.2 | 5.7 | 215.2 | 202 | 123 | 110 | 36 | 76 | 136 | 7 | 0 | 0 | 1 | 17 | 3 | 3 | 5.01 |
| CL | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 92 | 0 | 5 | 12 | 4.23 | .305 | 1.29 | 7.5 | 4.2 | 8.6 | 106.1 | 88 | 50 | 50 | 7 | 49 | 101 | 0 | 39 | 6 | 0 | 0 | 3 | 0 | 3.42 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 93 | 0 | 3 | 3 | 4.42 | .309 | 1.30 | 8.6 | 3.1 | 9.7 | 106.0 | 101 | 52 | 52 | 16 | 37 | 114 | 0 | 3 | 8 | 0 | 0 | 4 | 0 | 3.97 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 75 | 0 | 9 | 5 | 3.24 | .278 | 1.14 | 6.8 | 3.5 | 9.4 | 94.1 | 71 | 34 | 34 | 10 | 37 | 98 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 3.51 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 60 | 0 | 5 | 3 | 3.71 | .312 | 1.35 | 7.7 | 4.5 | 9.7 | 80.0 | 68 | 35 | 33 | 7 | 40 | 86 | 0 | 2 | 1 | 0 | 0 | 1 | 7 | 3.53 |