| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 33 | 33 | 10 | 15 | 3.98 | .285 | 1.19 | 8.9 | 1.9 | 7.8 | 251.0 | 247 | 116 | 111 | 28 | 52 | 218 | 6 | 0 | 0 | 2 | 20 | 1 | 8 | 3.35 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 32 | 32 | 16 | 8 | 3.52 | .306 | 1.30 | 9.5 | 2.3 | 4.5 | 245.2 | 258 | 104 | 96 | 18 | 62 | 122 | 8 | 0 | 0 | 1 | 22 | 5 | 4 | 3.78 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 31 | 31 | 10 | 14 | 5.45 | .344 | 1.55 | 11.0 | 3.0 | 4.4 | 206.1 | 252 | 130 | 125 | 23 | 68 | 100 | 6 | 0 | 0 | 2 | 15 | 4 | 4 | 4.53 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 30 | 30 | 12 | 14 | 4.71 | .333 | 1.48 | 10.1 | 3.2 | 3.5 | 225.2 | 253 | 120 | 118 | 20 | 81 | 88 | 10 | 0 | 0 | 0 | 11 | 4 | 2 | 4.51 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 79 | 0 | 6 | 4 | 2.90 | .278 | 1.12 | 7.4 | 2.7 | 8.1 | 96.1 | 79 | 32 | 31 | 7 | 29 | 86 | 0 | 11 | 1 | 0 | 0 | 3 | 1 | 3.16 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 46 | 0 | 8 | 4 | 3.24 | .289 | 1.20 | 7.4 | 3.4 | 7.4 | 50.0 | 41 | 19 | 18 | 5 | 19 | 41 | 0 | 8 | 5 | 0 | 0 | 1 | 0 | 3.86 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 27 | 0 | 1 | 2 | 3.48 | .301 | 1.26 | 9.3 | 2.0 | 7.3 | 31.0 | 32 | 13 | 12 | 2 | 7 | 25 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.00 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 30 | 0 | 1 | 0 | 4.41 | .307 | 1.33 | 9.0 | 3.2 | 8.5 | 34.2 | 34 | 17 | 17 | 8 | 12 | 32 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 5.24 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 1 | 0 | 0 | 0 | 0.00 | .333 | 1.50 | 9.0 | 9.0 | 9.0 | 1.1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 10 | 0 | 1 | 0 | 5.87 | .324 | 1.43 | 7.8 | 5.4 | 4.8 | 15.1 | 13 | 10 | 10 | 1 | 9 | 8 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.60 |