| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 29 | 29 | 7 | 12 | 3.95 | .282 | 1.17 | 8.0 | 2.5 | 9.2 | 177.2 | 158 | 83 | 78 | 24 | 49 | 180 | 0 | 0 | 0 | 0 | 19 | 2 | 0 | 3.59 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 28 | 28 | 11 | 11 | 4.47 | .307 | 1.30 | 8.5 | 3.3 | 9.3 | 171.0 | 161 | 89 | 85 | 23 | 62 | 177 | 2 | 0 | 0 | 0 | 13 | 4 | 4 | 3.84 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 28 | 28 | 11 | 7 | 5.01 | .307 | 1.32 | 8.1 | 3.8 | 5.4 | 156.1 | 140 | 91 | 87 | 27 | 66 | 94 | 2 | 0 | 0 | 0 | 14 | 2 | 2 | 5.35 |
| SP | Tesreau, J.Tesreau, Jeff >> | 27 | 1915 | R | 29 | 30 | 27 | 7 | 13 | 5.68 | .332 | 1.47 | 10.8 | 2.4 | 4.5 | 155.1 | 186 | 105 | 98 | 20 | 42 | 78 | 3 | 0 | 0 | 1 | 10 | 4 | 8 | 4.56 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 75 | 0 | 6 | 6 | 3.41 | .251 | 0.99 | 5.4 | 3.5 | 10.1 | 92.1 | 55 | 36 | 35 | 14 | 36 | 103 | 0 | 32 | 4 | 0 | 0 | 2 | 1 | 3.98 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 80 | 0 | 1 | 5 | 3.47 | .300 | 1.26 | 8.3 | 3.2 | 8.9 | 85.2 | 78 | 39 | 33 | 7 | 30 | 84 | 0 | 3 | 3 | 0 | 0 | 2 | 0 | 3.22 |