| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 28 | 28 | 9 | 11 | 4.02 | .317 | 1.37 | 8.0 | 4.3 | 7.7 | 168.0 | 149 | 80 | 75 | 12 | 81 | 144 | 1 | 0 | 0 | 1 | 18 | 4 | 4 | 3.73 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 28 | 28 | 14 | 10 | 5.07 | .325 | 1.44 | 10.8 | 2.2 | 5.2 | 163.1 | 196 | 100 | 92 | 15 | 40 | 95 | 4 | 0 | 0 | 0 | 14 | 0 | 0 | 3.77 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 26 | 26 | 14 | 4 | 2.77 | .284 | 1.18 | 6.8 | 3.9 | 3.9 | 169.0 | 127 | 63 | 52 | 9 | 73 | 74 | 2 | 0 | 0 | 0 | 19 | 1 | 1 | 4.13 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 62 | 0 | 5 | 2 | 2.07 | .269 | 1.09 | 5.8 | 4.0 | 10.2 | 65.1 | 42 | 15 | 15 | 5 | 29 | 74 | 0 | 40 | 1 | 0 | 0 | 1 | 2 | 3.11 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 76 | 0 | 6 | 2 | 3.16 | .295 | 1.23 | 8.8 | 2.3 | 7.3 | 74.0 | 72 | 34 | 26 | 6 | 19 | 60 | 0 | 4 | 4 | 0 | 0 | 2 | 0 | 3.28 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 53 | 0 | 3 | 2 | 2.49 | .309 | 1.32 | 7.2 | 4.9 | 4.9 | 50.2 | 40 | 16 | 14 | 4 | 27 | 27 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 4.64 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 30 | 0 | 1 | 3 | 6.10 | .372 | 1.74 | 9.9 | 5.8 | 8.1 | 31.0 | 34 | 22 | 21 | 2 | 20 | 28 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.06 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 2 | 0 | 0 | 0 | 0.82 | .283 | 1.09 | 5.7 | 4.1 | 10.6 | 11.0 | 7 | 3 | 1 | 0 | 5 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.27 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 7 | 1 | 1 | 1 | 4.61 | .305 | 1.32 | 11.1 | 1.4 | 5.5 | 13.2 | 16 | 7 | 7 | 1 | 2 | 8 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 3.23 |