| SP | Verlander, J.Verlander, Justin # >> | 28 | 2011 | R | 91 | 33 | 33 | 14 | 12 | 3.95 | .306 | 1.30 | 9.0 | 2.8 | 6.2 | 232.2 | 231 | 107 | 102 | 16 | 72 | 159 | 5 | 0 | 0 | 0 | 19 | 5 | 5 | 3.52 |
| SP | Skubal, T.Skubal, Tarik # >> | 27 | 2024 | L | 84 | 33 | 33 | 18 | 6 | 3.03 | .271 | 1.11 | 8.3 | 1.7 | 8.6 | 214.0 | 197 | 76 | 72 | 17 | 40 | 204 | 0 | 0 | 0 | 0 | 24 | 2 | 2 | 2.71 |
| SP | Flaherty, J.Flaherty, Jack >> | 28 | 2024 | R | 68 | 32 | 32 | 10 | 13 | 4.28 | .313 | 1.33 | 9.0 | 3.0 | 8.8 | 193.1 | 193 | 100 | 92 | 19 | 64 | 189 | 0 | 0 | 0 | 0 | 16 | 7 | 8 | 3.42 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 74 | 32 | 32 | 16 | 10 | 4.59 | .326 | 1.43 | 9.1 | 3.8 | 8.9 | 211.2 | 214 | 113 | 108 | 19 | 89 | 209 | 0 | 0 | 0 | 0 | 15 | 4 | 10 | 3.51 |
| SP | Fister, D.Fister, Doug >> | 27 | 2011 | R | 86 | 31 | 31 | 0 | 4 | 3.26 | .282 | 1.13 | 9.1 | 1.2 | 6.0 | 85.2 | 86 | 34 | 31 | 8 | 11 | 57 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 3.41 |
| CL | Greene, S.Greene, Shane † >> | 30 | 2019 | R | 78 | 68 | 0 | 3 | 6 | 2.73 | .265 | 1.08 | 5.9 | 3.9 | 8.5 | 69.1 | 45 | 24 | 21 | 5 | 30 | 65 | 0 | 45 | 4 | 0 | 0 | 0 | 0 | 3.36 |
| SU | Holton, T.Holton, Tyler >> | 28 | 2024 | L | 77 | 69 | 0 | 6 | 5 | 4.57 | .299 | 1.26 | 9.5 | 2.0 | 5.9 | 80.2 | 84 | 43 | 41 | 5 | 18 | 52 | 0 | 1 | 6 | 0 | 0 | 1 | 0 | 3.23 |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 71 | 81 | 0 | 6 | 2 | 2.34 | .295 | 1.24 | 6.4 | 4.8 | 9.6 | 65.1 | 46 | 17 | 17 | 4 | 35 | 69 | 0 | 2 | 0 | 0 | 0 | 1 | 4 | 3.34 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 64 | 93 | 0 | 7 | 2 | 2.44 | .283 | 1.16 | 7.1 | 3.3 | 5.3 | 107.0 | 85 | 30 | 29 | 5 | 39 | 63 | 0 | 0 | 2 | 0 | 0 | 3 | 7 | 3.61 |
| RP | Saucier, K.Saucier, Kevin >> | 25 | 1981 | L | 62 | 65 | 0 | 3 | 4 | 2.87 | .272 | 1.12 | 6.3 | 4.0 | 4.9 | 59.2 | 41 | 21 | 19 | 5 | 26 | 32 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 4.34 |
| RP | Rondon, B.Rondon, Bruce >> | 25 | 2016 | R | 59 | 75 | 0 | 5 | 5 | 3.74 | .301 | 1.29 | 7.8 | 3.9 | 8.2 | 65.0 | 56 | 29 | 27 | 6 | 28 | 59 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 3.68 |
| RP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 50 | 50 | 0 | 0 | 4 | 4.89 | .290 | 1.23 | 8.4 | 2.7 | 5.5 | 57.0 | 53 | 33 | 31 | 9 | 17 | 35 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.72 |