| SP | Steele, E.Steele, Elmer † # >> | 22 | 1908 | R | 77 | 18 | 18 | 11 | 4 | 2.95 | .273 | 1.12 | 8.1 | 2.0 | 3.3 | 134.1 | 120 | 51 | 44 | 11 | 30 | 49 | 5 | 0 | 0 | 3 | 11 | 1 | 0 | 4.03 |
| SP | Martinez, P.Martinez, Pedro # >> | 30 | 2001 | R | 75 | 17 | 17 | 6 | 6 | 5.72 | .351 | 1.57 | 10.8 | 3.4 | 9.2 | 96.0 | 115 | 65 | 61 | 11 | 36 | 98 | 1 | 0 | 0 | 1 | 7 | 5 | 1 | 3.73 |
| SP | Morgan, C.Morgan, Cy # >> | 29 | 1907 | R | 57 | 16 | 16 | 7 | 7 | 5.44 | .337 | 1.52 | 9.6 | 4.1 | 5.5 | 97.2 | 104 | 63 | 59 | 10 | 44 | 59 | 2 | 0 | 0 | 0 | 7 | 1 | 0 | 4.52 |
| SP | Buchholz, C.Buchholz, Clay >> | 29 | 2013 | R | 47 | 16 | 15 | 8 | 2 | 4.07 | .345 | 1.55 | 9.6 | 4.5 | 5.3 | 101.2 | 108 | 54 | 46 | 6 | 50 | 60 | 1 | 0 | 0 | 1 | 9 | 3 | 3 | 4.16 |
| SP | Shore, E.Shore, Ernie # >> | 23 | 1914 | R | 40 | 17 | 16 | 6 | 7 | 5.61 | .343 | 1.51 | 10.1 | 3.5 | 4.1 | 102.2 | 115 | 68 | 64 | 9 | 40 | 46 | 2 | 0 | 0 | 1 | 5 | 6 | 2 | 4.60 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 42 | 0 | 3 | 0 | 2.24 | .259 | 1.03 | 6.8 | 2.6 | 8.8 | 56.1 | 42 | 16 | 14 | 4 | 16 | 55 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 2.88 |
| RP | Papelbon, J.Papelbon, Jonathan † >> | 27 | 2007 | R | 95 | 39 | 0 | 4 | 0 | 1.91 | .246 | 0.98 | 5.9 | 2.9 | 9.0 | 47.0 | 31 | 10 | 10 | 2 | 15 | 47 | 0 | 7 | 2 | 0 | 0 | 0 | 0 | 2.51 |
| RP | Brasier, R.Brasier, Ryan >> | 30 | 2018 | R | 84 | 24 | 0 | 4 | 2 | 3.07 | .279 | 1.13 | 6.8 | 3.4 | 5.0 | 29.1 | 22 | 10 | 10 | 3 | 11 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.48 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 67 | 14 | 0 | 1 | 0 | 2.86 | .267 | 1.05 | 8.2 | 1.2 | 7.8 | 22.0 | 20 | 7 | 7 | 3 | 3 | 19 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.59 |