| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 28 | 28 | 8 | 14 | 3.92 | .296 | 1.25 | 7.8 | 3.5 | 8.8 | 193.0 | 167 | 89 | 84 | 28 | 75 | 188 | 2 | 0 | 0 | 0 | 18 | 1 | 2 | 4.12 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 27 | 27 | 12 | 6 | 4.16 | .300 | 1.26 | 8.8 | 2.5 | 4.2 | 147.0 | 144 | 73 | 68 | 13 | 41 | 68 | 0 | 0 | 0 | 0 | 9 | 4 | 4 | 4.14 |
| SP | Krause, H.Krause, Harry # >> | 21 | 1909 | L | 72 | 27 | 27 | 8 | 17 | 5.70 | .341 | 1.53 | 10.2 | 3.6 | 4.7 | 169.0 | 191 | 113 | 107 | 25 | 67 | 89 | 1 | 0 | 0 | 0 | 12 | 4 | 2 | 5.13 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 27 | 27 | 8 | 10 | 3.99 | .298 | 1.25 | 8.2 | 3.1 | 8.4 | 189.1 | 172 | 95 | 84 | 23 | 65 | 177 | 3 | 0 | 0 | 1 | 18 | 4 | 7 | 3.80 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 64 | 25 | 25 | 16 | 6 | 3.44 | .283 | 1.16 | 8.1 | 2.4 | 5.6 | 188.1 | 169 | 75 | 72 | 14 | 50 | 116 | 4 | 0 | 0 | 1 | 19 | 4 | 1 | 3.60 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 72 | 0 | 5 | 4 | 3.76 | .277 | 1.14 | 8.4 | 1.9 | 9.3 | 95.2 | 89 | 40 | 40 | 14 | 20 | 98 | 0 | 6 | 3 | 0 | 0 | 1 | 3 | 3.52 |
| RP | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 85 | 63 | 0 | 3 | 5 | 3.16 | .282 | 1.17 | 8.3 | 2.3 | 9.1 | 79.2 | 73 | 32 | 28 | 11 | 20 | 80 | 0 | 12 | 2 | 0 | 0 | 1 | 2 | 3.58 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 46 | 0 | 5 | 1 | 3.93 | .295 | 1.18 | 7.3 | 3.4 | 4.4 | 68.2 | 55 | 32 | 30 | 4 | 26 | 33 | 0 | 8 | 1 | 0 | 0 | 5 | 4 | 4.16 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 53 | 24 | 0 | 0 | 1 | 6.92 | .405 | 1.88 | 11.1 | 5.9 | 6.9 | 26.0 | 32 | 22 | 20 | 5 | 17 | 20 | 0 | 0 | 1 | 0 | 0 | 4 | 3 | 6.38 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 1 | 1 | 0 | 1 | 15.75 | .520 | 3.25 | 27.0 | 2.3 | 6.8 | 4.0 | 12 | 7 | 7 | 1 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.50 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 3 | 0 | 0 | 1 | 11.57 | .533 | 3.43 | 22.5 | 13.5 | 13.5 | 2.1 | 5 | 3 | 3 | 1 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.00 |