| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 38 | 38 | 14 | 15 | 3.26 | .262 | 1.05 | 6.8 | 2.7 | 7.0 | 240.0 | 181 | 88 | 87 | 21 | 71 | 187 | 2 | 0 | 0 | 1 | 28 | 4 | 8 | 3.52 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 36 | 36 | 19 | 9 | 3.11 | .273 | 1.10 | 7.3 | 2.5 | 4.9 | 234.1 | 191 | 87 | 81 | 19 | 66 | 127 | 1 | 0 | 0 | 0 | 26 | 7 | 3 | 3.91 |
| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1909 | R | 86 | 35 | 35 | 17 | 12 | 3.33 | .268 | 1.09 | 7.7 | 2.1 | 4.6 | 235.1 | 200 | 92 | 87 | 22 | 56 | 120 | 4 | 0 | 0 | 2 | 22 | 2 | 3 | 3.94 |
| SP | Fernandez, J.Fernandez, Jose † # >> | 21 | 2013 | R | 76 | 34 | 34 | 20 | 7 | 3.00 | .260 | 1.04 | 6.3 | 3.0 | 8.0 | 222.0 | 156 | 76 | 74 | 21 | 75 | 197 | 1 | 0 | 0 | 1 | 25 | 3 | 3 | 3.51 |
| CL | Kimbrel, C.Kimbrel, Craig $ >> | 24 | 2012 | R | 100 | 94 | 0 | 4 | 3 | 2.70 | .240 | 0.93 | 6.2 | 2.2 | 9.6 | 130.0 | 89 | 40 | 39 | 14 | 32 | 138 | 0 | 15 | 4 | 0 | 0 | 2 | 8 | 3.06 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 63 | 0 | 4 | 4 | 3.70 | .304 | 1.29 | 8.6 | 3.2 | 9.4 | 65.2 | 62 | 30 | 27 | 9 | 23 | 68 | 0 | 6 | 3 | 0 | 0 | 1 | 1 | 3.82 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 16 | 0 | 0 | 1 | 4.40 | .386 | 1.88 | 9.0 | 8.4 | 8.4 | 14.1 | 14 | 8 | 7 | 1 | 13 | 13 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 4.86 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 6 | 0 | 0 | 2 | 14.85 | .429 | 2.25 | 19.5 | 3.0 | 9.0 | 6.2 | 13 | 11 | 11 | 1 | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Radatz, D.Radatz, Dick >> | 27 | 1964 | R | 37 | 4 | 0 | 1 | 0 | 1.08 | .265 | 1.08 | 4.5 | 5.6 | 9.0 | 8.1 | 4 | 1 | 1 | 0 | 5 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.88 |