| SP | Sanchez, A.Sanchez, Anibal >> | 22 | 2006 | R | 88 | 33 | 33 | 6 | 16 | 4.51 | .318 | 1.35 | 8.7 | 3.5 | 6.1 | 209.2 | 202 | 113 | 105 | 32 | 82 | 141 | 0 | 0 | 0 | 0 | 17 | 9 | 4 | 4.95 |
| SP | Schilling, C.Schilling, Curt >> | 40 | 2006 | R | 64 | 32 | 32 | 12 | 9 | 5.46 | .343 | 1.53 | 10.9 | 2.8 | 6.8 | 196.0 | 238 | 123 | 119 | 22 | 62 | 148 | 1 | 0 | 0 | 0 | 13 | 7 | 2 | 4.01 |
| SP | Maddux, G.Maddux, Greg >> | 40 | 2006 | R | 56 | 32 | 32 | 7 | 15 | 5.45 | .316 | 1.36 | 9.9 | 2.3 | 5.5 | 200.0 | 221 | 122 | 121 | 30 | 51 | 122 | 1 | 0 | 0 | 0 | 14 | 5 | 0 | 4.57 |
| RP | Reyes, D.Reyes, Dennys >> | 29 | 2006 | L | 94 | 92 | 0 | 7 | 7 | 3.29 | .293 | 1.23 | 7.5 | 3.6 | 6.5 | 139.2 | 116 | 57 | 51 | 14 | 56 | 101 | 0 | 5 | 9 | 0 | 0 | 2 | 8 | 4.11 |
| RP | Turnbow, D.Turnbow, Derrick † >> | 28 | 2006 | R | 13 | 67 | 0 | 6 | 4 | 3.13 | .317 | 1.33 | 7.5 | 4.5 | 9.6 | 74.2 | 62 | 28 | 26 | 5 | 37 | 79 | 0 | 5 | 3 | 0 | 0 | 5 | 8 | 3.45 |