| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 100 | 9 | 9 | 1 | 3 | 4.34 | .291 | 1.21 | 8.3 | 2.7 | 9.5 | 37.1 | 34 | 24 | 18 | 6 | 11 | 39 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.97 |
| SP | Smoltz, J.Smoltz, John >> | 39 | 2006 | R | 82 | 9 | 9 | 4 | 4 | 4.52 | .351 | 1.59 | 11.2 | 3.2 | 6.8 | 61.2 | 76 | 34 | 31 | 4 | 22 | 46 | 1 | 0 | 0 | 0 | 5 | 2 | 2 | 3.52 |
| SP | Buchholz, T.Buchholz, Taylor >> | 25 | 2006 | R | 68 | 9 | 9 | 3 | 3 | 3.24 | .312 | 1.36 | 9.5 | 2.7 | 7.2 | 50.0 | 53 | 18 | 18 | 6 | 15 | 40 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 3.86 |
| SP | Capuano, C.Capuano, Chris >> | 28 | 2006 | L | 60 | 10 | 9 | 3 | 5 | 5.95 | .359 | 1.64 | 12.5 | 2.3 | 5.6 | 59.0 | 82 | 43 | 39 | 7 | 15 | 37 | 0 | 0 | 0 | 0 | 4 | 2 | 4 | 4.15 |
| RP | Wainwright, A.Wainwright, Adam >> | 25 | 2006 | R | 79 | 26 | 0 | 4 | 0 | 3.05 | .277 | 1.15 | 8.3 | 2.1 | 9.0 | 38.1 | 35 | 13 | 13 | 3 | 9 | 38 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.74 |
| CL | Street, H.Street, Huston >> | 23 | 2006 | R | 75 | 16 | 0 | 0 | 1 | 2.87 | .397 | 1.85 | 10.2 | 7.2 | 7.2 | 15.2 | 17 | 6 | 5 | 0 | 12 | 12 | 0 | 8 | 2 | 0 | 0 | 2 | 0 | 4.20 |
| RP | Heilman, A.Heilman, Aaron >> | 28 | 2006 | R | 74 | 26 | 0 | 2 | 0 | 4.60 | .338 | 1.50 | 9.9 | 3.7 | 5.3 | 29.1 | 32 | 15 | 15 | 4 | 12 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.97 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 87 | 10 | 0 | 1 | 0 | 1.46 | .339 | 1.54 | 8.3 | 6.0 | 9.8 | 12.1 | 11 | 2 | 2 | 0 | 8 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.83 |