| SP | Weaver, J.Weaver, Jered † $$ >> | 24 | 2006 | R | 98 | 17 | 17 | 12 | 1 | 2.41 | .283 | 1.17 | 7.5 | 3.1 | 6.0 | 123.0 | 102 | 33 | 33 | 10 | 42 | 82 | 0 | 0 | 0 | 0 | 14 | 2 | 0 | 3.80 |
| SP | Kazmir, S.Kazmir, Scott >> | 22 | 2006 | L | 75 | 16 | 16 | 3 | 4 | 4.65 | .339 | 1.54 | 9.6 | 4.2 | 7.4 | 89.0 | 95 | 49 | 46 | 6 | 42 | 73 | 0 | 0 | 0 | 0 | 8 | 0 | 9 | 3.65 |
| SP | Olsen, S.Olsen, Scott † >> | 22 | 2006 | L | 66 | 17 | 16 | 8 | 2 | 2.77 | .308 | 1.32 | 7.7 | 4.3 | 6.8 | 87.2 | 74 | 29 | 27 | 4 | 42 | 66 | 0 | 0 | 0 | 0 | 6 | 1 | 3 | 3.56 |
| SP | Hernandez, O.Hernandez, Orlando # >> | 41 | 2006 | R | 51 | 16 | 16 | 7 | 2 | 4.12 | .328 | 1.43 | 8.4 | 4.6 | 8.8 | 87.1 | 81 | 44 | 40 | 9 | 44 | 85 | 0 | 0 | 0 | 0 | 3 | 3 | 3 | 4.01 |
| RP | Cordero, C.Cordero, Chad >> | 24 | 2006 | R | 83 | 45 | 0 | 4 | 2 | 3.66 | .270 | 1.08 | 7.7 | 2.0 | 8.3 | 64.0 | 55 | 29 | 26 | 4 | 14 | 59 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 2.72 |
| RP | League, B.League, Brandon >> | 23 | 2006 | R | 82 | 39 | 0 | 2 | 3 | 4.11 | .303 | 1.26 | 9.6 | 1.8 | 5.7 | 46.0 | 49 | 24 | 21 | 5 | 9 | 29 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 3.87 |
| RP | Wainwright, A.Wainwright, Adam >> | 25 | 2006 | R | 79 | 38 | 0 | 2 | 1 | 7.11 | .348 | 1.58 | 12.1 | 2.3 | 5.5 | 44.1 | 59 | 37 | 35 | 11 | 11 | 27 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 5.84 |
| RP | Aardsma, D.Aardsma, David >> | 25 | 2006 | R | 63 | 30 | 0 | 5 | 6 | 10.31 | .433 | 2.29 | 13.7 | 7.4 | 8.1 | 29.2 | 44 | 35 | 34 | 5 | 24 | 26 | 0 | 0 | 5 | 0 | 0 | 0 | 3 | 5.93 |
| RP | Tankersley, T.Tankersley, Taylor >> | 23 | 2006 | L | 43 | 28 | 0 | 0 | 0 | 2.86 | .292 | 1.13 | 5.8 | 4.5 | 9.3 | 28.1 | 18 | 13 | 9 | 1 | 14 | 29 | 0 | 2 | 1 | 0 | 0 | 3 | 2 | 3.21 |
| CL | Saito, T.Saito, Takashi † $ >> | 36 | 2006 | R | 97 | 41 | 0 | 2 | 3 | 3.21 | .274 | 1.13 | 7.7 | 2.7 | 12.1 | 47.2 | 40 | 18 | 17 | 5 | 14 | 63 | 0 | 21 | 5 | 0 | 0 | 0 | 3 | 2.60 |