| SP | Hamels, C.Hamels, Cole >> | 23 | 2006 | L | 83 | 14 | 14 | 1 | 6 | 5.24 | .376 | 1.79 | 11.7 | 4.4 | 8.6 | 67.0 | 87 | 43 | 39 | 12 | 33 | 64 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.94 |
| SP | Martinez, P.Martinez, Pedro # >> | 35 | 2006 | R | 96 | 14 | 14 | 5 | 5 | 4.97 | .305 | 1.29 | 9.5 | 2.2 | 9.1 | 70.2 | 74 | 40 | 39 | 10 | 17 | 71 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 3.64 |
| SP | Johnson, R.Johnson, Randy >> | 43 | 2006 | L | 73 | 13 | 13 | 5 | 3 | 4.32 | .334 | 1.49 | 10.2 | 3.2 | 7.2 | 75.0 | 85 | 36 | 36 | 8 | 27 | 60 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 3.91 |
| SP | Willis, D.Willis, Dontrelle >> | 24 | 2006 | L | 22 | 14 | 11 | 3 | 2 | 5.92 | .367 | 1.70 | 11.0 | 4.4 | 5.5 | 59.1 | 72 | 39 | 39 | 6 | 29 | 36 | 0 | 1 | 1 | 0 | 2 | 2 | 1 | 4.68 |
| RP | Wheeler, D.Wheeler, Dan >> | 29 | 2006 | R | 80 | 34 | 0 | 2 | 2 | 2.74 | .264 | 1.07 | 6.4 | 3.3 | 7.2 | 49.1 | 35 | 16 | 15 | 4 | 18 | 39 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.57 |
| RP | Oliver, D.Oliver, Darren >> | 36 | 2006 | L | 73 | 37 | 0 | 2 | 3 | 3.83 | .349 | 1.58 | 10.7 | 3.6 | 6.2 | 42.1 | 50 | 21 | 18 | 7 | 17 | 29 | 0 | 5 | 1 | 0 | 0 | 1 | 2 | 5.07 |
| RP | Weathers, D.Weathers, Dave >> | 37 | 2006 | R | 49 | 26 | 0 | 1 | 1 | 1.64 | .263 | 1.07 | 7.1 | 2.6 | 4.5 | 38.1 | 30 | 10 | 7 | 3 | 11 | 19 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 3.89 |
| RP | Marte, D.Marte, Damaso >> | 31 | 2006 | L | 33 | 18 | 0 | 1 | 0 | 2.38 | .320 | 1.37 | 7.4 | 5.3 | 9.4 | 22.2 | 18 | 6 | 6 | 1 | 13 | 23 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 3.41 |