| SP | Clemens, R.Clemens, Roger >> | 44 | 2006 | R | 97 | 6 | 6 | 2 | 2 | 3.00 | .250 | 1.00 | 6.8 | 2.2 | 6.8 | 33.0 | 25 | 13 | 11 | 3 | 8 | 25 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 3.39 |
| SP | Hamels, C.Hamels, Cole >> | 23 | 2006 | L | 83 | 5 | 5 | 2 | 2 | 6.20 | .368 | 1.66 | 11.6 | 3.8 | 7.5 | 24.2 | 31 | 17 | 17 | 8 | 10 | 20 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 7.17 |
| SP | Johnson, R.Johnson, Randy # >> | 43 | 2006 | L | 73 | 5 | 5 | 2 | 1 | 5.34 | .316 | 1.35 | 8.7 | 3.6 | 6.6 | 30.1 | 29 | 18 | 18 | 4 | 12 | 22 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 4.57 |
| SP | Escobar, K.Escobar, Kelvim >> | 30 | 2006 | R | 53 | 5 | 5 | 0 | 1 | 8.44 | .389 | 1.91 | 13.5 | 4.2 | 8.0 | 26.2 | 39 | 29 | 25 | 6 | 12 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 5.62 |
| SU | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 87 | 10 | 0 | 0 | 1 | 3.38 | .286 | 1.20 | 6.9 | 4.2 | 11.8 | 13.1 | 10 | 6 | 5 | 2 | 6 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.77 |
| RP | Rodney, F.Rodney, Fernando >> | 29 | 2006 | R | 81 | 15 | 0 | 2 | 0 | 4.50 | .344 | 1.57 | 8.4 | 5.8 | 8.4 | 14.0 | 13 | 8 | 7 | 2 | 9 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.93 |
| RP | Wheeler, D.Wheeler, Dan >> | 29 | 2006 | R | 80 | 13 | 0 | 2 | 0 | 1.46 | .229 | 0.89 | 6.8 | 1.5 | 9.8 | 12.1 | 9 | 2 | 2 | 2 | 2 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| RP | Oliver, D.Oliver, Darren >> | 36 | 2006 | L | 73 | 20 | 0 | 2 | 1 | 2.57 | .288 | 1.14 | 7.7 | 2.6 | 6.4 | 14.0 | 12 | 4 | 4 | 1 | 4 | 10 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 3.57 |
| RP | Qualls, C.Qualls, Chad >> | 28 | 2006 | R | 66 | 10 | 0 | 3 | 0 | 4.38 | .288 | 1.22 | 9.0 | 2.3 | 6.0 | 12.1 | 12 | 6 | 6 | 1 | 3 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| RP | Walker, J.Walker, Jamie >> | 35 | 2006 | L | 58 | 15 | 0 | 1 | 0 | 0.00 | .176 | 0.64 | 5.0 | 1.0 | 10.0 | 9.1 | 5 | 0 | 0 | 0 | 1 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.11 |