| SP | Hamels, C.Hamels, Cole # >> | 23 | 2006 | L | 83 | 16 | 16 | 3 | 5 | 4.63 | .320 | 1.40 | 9.3 | 3.4 | 9.8 | 83.2 | 86 | 46 | 43 | 12 | 31 | 90 | 0 | 0 | 0 | 0 | 6 | 1 | 3 | 3.87 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 100 | 16 | 16 | 4 | 0 | 2.25 | .239 | 0.92 | 6.8 | 1.5 | 9.8 | 72.0 | 54 | 18 | 18 | 9 | 12 | 78 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 3.04 |
| SP | Rogers, K.Rogers, Kenny >> | 42 | 2006 | L | 65 | 16 | 16 | 8 | 7 | 5.10 | .345 | 1.58 | 10.2 | 4.0 | 5.3 | 90.0 | 102 | 57 | 51 | 12 | 40 | 53 | 1 | 0 | 0 | 1 | 7 | 0 | 2 | 4.89 |
| SP | Wakefield, T.Wakefield, Tim >> | 40 | 2006 | R | 46 | 17 | 16 | 6 | 5 | 6.16 | .366 | 1.71 | 10.4 | 5.1 | 5.0 | 87.2 | 101 | 61 | 60 | 9 | 49 | 48 | 0 | 0 | 0 | 0 | 5 | 2 | 4 | 5.00 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 24 | 2006 | R | 93 | 46 | 0 | 4 | 4 | 3.76 | .295 | 1.22 | 7.3 | 3.8 | 9.6 | 64.2 | 52 | 27 | 27 | 7 | 27 | 68 | 0 | 2 | 3 | 0 | 0 | 2 | 8 | 3.66 |
| RP | Springer, R.Springer, Russ >> | 38 | 2006 | R | 88 | 46 | 0 | 2 | 1 | 3.55 | .308 | 1.29 | 8.3 | 3.3 | 6.1 | 66.0 | 61 | 27 | 26 | 10 | 24 | 45 | 0 | 7 | 2 | 0 | 0 | 3 | 2 | 4.83 |
| RP | Wheeler, D.Wheeler, Dan >> | 29 | 2006 | R | 80 | 30 | 0 | 2 | 0 | 5.19 | .388 | 1.85 | 11.4 | 5.6 | 7.1 | 34.2 | 43 | 21 | 20 | 4 | 21 | 27 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 4.97 |
| RP | Otsuka, A.Otsuka, Akinori >> | 34 | 2006 | R | 76 | 27 | 0 | 3 | 0 | 6.14 | .338 | 1.50 | 11.2 | 2.5 | 6.5 | 29.1 | 36 | 21 | 20 | 7 | 8 | 21 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 5.62 |
| RP | Sanchez, D.Sanchez, Duaner >> | 27 | 2006 | R | 72 | 25 | 0 | 6 | 1 | 3.82 | .343 | 1.53 | 8.4 | 5.7 | 6.6 | 30.2 | 28 | 13 | 13 | 3 | 19 | 22 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.83 |
| RP | Britton, C.Britton, Chris >> | 24 | 2006 | R | 68 | 20 | 0 | 0 | 0 | 1.71 | .255 | 0.95 | 5.5 | 3.1 | 5.9 | 26.1 | 16 | 5 | 5 | 0 | 9 | 17 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 2.96 |