| SP | Mussina, M.Mussina, Mike >> | 38 | 2006 | R | 92 | 6 | 6 | 3 | 1 | 2.81 | .269 | 1.08 | 7.9 | 2.0 | 7.7 | 41.2 | 36 | 13 | 13 | 2 | 9 | 35 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 2.66 |
| SP | Smoltz, J.Smoltz, John >> | 39 | 2006 | R | 82 | 5 | 5 | 1 | 2 | 6.25 | .362 | 1.67 | 12.5 | 2.9 | 5.5 | 31.2 | 43 | 23 | 22 | 4 | 10 | 19 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 4.52 |
| SP | Zambrano, C.Zambrano, Carlos $$ >> | 25 | 2006 | R | 77 | 5 | 5 | 3 | 1 | 5.72 | .361 | 1.62 | 9.6 | 5.1 | 6.1 | 28.1 | 30 | 21 | 18 | 6 | 16 | 19 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 6.36 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 28 | 2006 | L | 56 | 14 | 0 | 3 | 0 | 4.60 | .347 | 1.47 | 7.8 | 6.0 | 12.0 | 15.2 | 13 | 8 | 8 | 4 | 10 | 20 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 6.20 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 98 | 16 | 0 | 1 | 3 | 5.68 | .288 | 1.21 | 7.6 | 3.3 | 8.5 | 19.0 | 16 | 12 | 12 | 4 | 7 | 18 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 4.95 |
| RP | Fuentes, B.Fuentes, Brian >> | 31 | 2006 | L | 84 | 11 | 0 | 1 | 0 | 5.40 | .352 | 1.54 | 9.0 | 5.7 | 10.6 | 11.2 | 11 | 7 | 7 | 0 | 7 | 13 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.82 |
| RP | Broxton, J.Broxton, Jonathan >> | 22 | 2006 | R | 78 | 8 | 0 | 2 | 1 | 0.79 | .128 | 0.44 | 2.5 | 1.6 | 11.5 | 11.1 | 3 | 1 | 1 | 0 | 2 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| RP | Aardsma, D.Aardsma, David >> | 25 | 2006 | R | 63 | 5 | 0 | 0 | 0 | 3.38 | .333 | 1.31 | 10.8 | 1.8 | 7.2 | 5.1 | 6 | 2 | 2 | 1 | 1 | 4 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 5.20 |
| RP | Correia, K.Correia, Kevin >> | 26 | 2006 | R | 51 | 4 | 0 | 0 | 1 | 6.75 | .333 | 1.50 | 9.0 | 4.5 | 11.3 | 4.0 | 4 | 3 | 3 | 1 | 2 | 5 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.25 |
| RP | Calero, K.Calero, Kiko >> | 31 | 2006 | R | 62 | 7 | 0 | 0 | 0 | 3.38 | .400 | 1.88 | 6.8 | 10.1 | 4.5 | 8.0 | 6 | 3 | 3 | 1 | 9 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 7.38 |