| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 32 | 32 | 11 | 18 | 5.03 | .299 | 1.27 | 9.1 | 2.4 | 4.3 | 223.2 | 225 | 126 | 125 | 29 | 59 | 107 | 6 | 0 | 0 | 1 | 14 | 2 | 2 | 4.55 |
| SP | Gooden, D.Gooden, Dwight # >> | 21 | 1985 | R | 68 | 31 | 31 | 14 | 11 | 4.25 | .313 | 1.33 | 9.2 | 2.7 | 6.6 | 231.0 | 237 | 122 | 109 | 31 | 70 | 169 | 6 | 0 | 0 | 1 | 14 | 9 | 7 | 4.31 |
| SP | Drysdale, D.Drysdale, Don # >> | 28 | 1964 | R | 58 | 31 | 31 | 15 | 11 | 4.44 | .301 | 1.29 | 8.6 | 3.0 | 5.5 | 233.1 | 222 | 123 | 115 | 27 | 78 | 142 | 12 | 0 | 0 | 4 | 14 | 1 | 5 | 4.30 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 82 | 0 | 4 | 7 | 3.61 | .295 | 1.26 | 8.7 | 2.7 | 8.9 | 94.2 | 91 | 40 | 38 | 9 | 28 | 93 | 0 | 9 | 5 | 0 | 0 | 0 | 2 | 3.16 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 43 | 0 | 3 | 3 | 3.98 | .287 | 1.21 | 7.3 | 3.6 | 9.2 | 43.0 | 35 | 20 | 19 | 7 | 17 | 44 | 0 | 5 | 4 | 0 | 0 | 0 | 2 | 4.26 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 30 | 0 | 2 | 0 | 2.65 | .263 | 1.04 | 7.5 | 1.9 | 10.0 | 37.1 | 31 | 11 | 11 | 2 | 8 | 41 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 2.22 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 24 | 0 | 0 | 4 | 6.88 | .404 | 2.04 | 10.5 | 8.0 | 7.5 | 35.1 | 41 | 27 | 27 | 8 | 31 | 29 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 6.97 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 24 | 0 | 0 | 0 | 1.63 | .265 | 1.05 | 7.0 | 2.7 | 7.3 | 27.2 | 21 | 5 | 5 | 3 | 8 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.81 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 5 | 1 | 2 | 2 | 5.40 | .348 | 1.60 | 10.8 | 3.6 | 7.2 | 15.0 | 18 | 11 | 9 | 1 | 6 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.47 |