| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 8 | 15 | 4.06 | .317 | 1.36 | 9.4 | 2.8 | 8.2 | 223.2 | 234 | 109 | 101 | 33 | 70 | 204 | 1 | 0 | 0 | 0 | 21 | 7 | 4 | 4.13 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 32 | 32 | 13 | 15 | 5.49 | .323 | 1.40 | 10.2 | 2.4 | 5.3 | 211.1 | 239 | 132 | 129 | 37 | 57 | 124 | 10 | 0 | 0 | 2 | 9 | 7 | 0 | 5.01 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 66 | 31 | 31 | 9 | 12 | 4.11 | .313 | 1.35 | 8.8 | 3.4 | 5.5 | 221.1 | 215 | 109 | 101 | 18 | 84 | 136 | 3 | 0 | 0 | 2 | 16 | 3 | 7 | 4.01 |
| RP | Jansen, K.Jansen, Kenley # >> | 28 | 2016 | R | 97 | 77 | 0 | 6 | 9 | 3.92 | .264 | 1.05 | 6.9 | 2.5 | 8.8 | 103.1 | 79 | 47 | 45 | 13 | 29 | 101 | 0 | 9 | 3 | 0 | 0 | 3 | 1 | 3.61 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 63 | 0 | 1 | 5 | 3.75 | .286 | 1.16 | 8.0 | 2.6 | 7.8 | 81.2 | 72 | 36 | 34 | 12 | 23 | 70 | 0 | 8 | 3 | 0 | 0 | 3 | 4 | 4.16 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 57 | 0 | 1 | 8 | 4.15 | .286 | 1.19 | 8.3 | 2.6 | 9.0 | 60.2 | 55 | 28 | 28 | 10 | 17 | 60 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 4.07 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 47 | 0 | 4 | 4 | 4.58 | .329 | 1.42 | 7.2 | 5.6 | 5.5 | 94.1 | 75 | 48 | 48 | 7 | 59 | 57 | 0 | 2 | 1 | 0 | 0 | 5 | 6 | 4.80 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |