| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 23 | 23 | 12 | 10 | 4.23 | .299 | 1.25 | 8.3 | 2.9 | 7.2 | 168.0 | 155 | 84 | 79 | 19 | 55 | 135 | 7 | 0 | 0 | 1 | 13 | 5 | 5 | 3.93 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 82 | 24 | 24 | 6 | 9 | 5.11 | .310 | 1.34 | 9.9 | 2.1 | 5.0 | 162.0 | 179 | 95 | 92 | 20 | 38 | 90 | 4 | 0 | 0 | 1 | 9 | 1 | 6 | 4.22 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 24 | 24 | 12 | 12 | 4.41 | .326 | 1.44 | 10.4 | 2.6 | 4.4 | 173.1 | 200 | 95 | 85 | 17 | 50 | 85 | 7 | 0 | 0 | 1 | 11 | 2 | 10 | 4.20 |
| SP | Overall, O.Overall, Orval # >> | 28 | 1909 | R | 57 | 23 | 23 | 9 | 12 | 4.97 | .320 | 1.38 | 9.8 | 2.7 | 5.3 | 164.2 | 178 | 95 | 91 | 16 | 50 | 97 | 7 | 0 | 0 | 0 | 9 | 5 | 2 | 4.09 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 63 | 0 | 1 | 1 | 3.15 | .300 | 1.26 | 7.0 | 4.4 | 6.9 | 80.0 | 62 | 28 | 28 | 6 | 39 | 61 | 0 | 7 | 0 | 0 | 0 | 2 | 0 | 3.99 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 44 | 0 | 1 | 3 | 4.08 | .326 | 1.42 | 7.6 | 5.1 | 7.5 | 53.0 | 45 | 25 | 24 | 11 | 30 | 44 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 5.85 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 37 | 0 | 4 | 2 | 3.70 | .354 | 1.60 | 10.1 | 4.4 | 10.3 | 41.1 | 46 | 19 | 17 | 4 | 20 | 47 | 0 | 5 | 3 | 0 | 0 | 2 | 2 | 3.59 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 24 | 0 | 1 | 1 | 3.99 | .279 | 1.16 | 7.8 | 2.8 | 7.8 | 29.1 | 25 | 13 | 13 | 4 | 9 | 25 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.00 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 11 | 2 | 2 | 1 | 4.88 | .327 | 1.46 | 9.0 | 4.1 | 7.5 | 24.0 | 24 | 13 | 13 | 2 | 11 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.79 |