| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 98 | 33 | 33 | 14 | 16 | 3.45 | .269 | 1.09 | 7.6 | 2.2 | 8.2 | 247.2 | 208 | 100 | 95 | 24 | 61 | 226 | 15 | 0 | 0 | 3 | 20 | 4 | 8 | 3.22 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 32 | 32 | 15 | 13 | 4.60 | .303 | 1.29 | 8.9 | 2.7 | 4.5 | 219.0 | 216 | 122 | 112 | 19 | 66 | 109 | 5 | 0 | 0 | 0 | 16 | 4 | 5 | 4.09 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 30 | 30 | 10 | 12 | 5.69 | .345 | 1.55 | 9.6 | 4.5 | 4.9 | 175.2 | 186 | 120 | 111 | 21 | 87 | 95 | 1 | 0 | 0 | 0 | 13 | 4 | 1 | 5.03 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 86 | 0 | 6 | 7 | 3.74 | .306 | 1.30 | 7.3 | 4.4 | 8.5 | 130.0 | 105 | 63 | 54 | 14 | 64 | 123 | 0 | 12 | 2 | 0 | 0 | 3 | 0 | 4.05 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 62 | 0 | 2 | 5 | 4.08 | .292 | 1.21 | 9.6 | 1.3 | 7.7 | 75.0 | 80 | 36 | 34 | 13 | 11 | 64 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 4.07 |
| RP | Zimmerman, J.Zimmerman, Jeff # >> | 27 | 1999 | R | 70 | 54 | 0 | 2 | 3 | 3.66 | .306 | 1.29 | 8.2 | 3.4 | 4.6 | 59.0 | 54 | 25 | 24 | 7 | 22 | 30 | 0 | 8 | 1 | 0 | 0 | 2 | 2 | 4.75 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 3 | 0 | 0 | 0 | 1.23 | .290 | 1.23 | 5.1 | 6.4 | 3.9 | 7.1 | 4 | 1 | 1 | 0 | 5 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.29 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 19 | 0 | 1 | 1 | 4.02 | .339 | 1.54 | 8.3 | 5.6 | 4.3 | 40.1 | 37 | 24 | 18 | 4 | 25 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 5.23 |