| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 33 | 33 | 12 | 12 | 4.87 | .319 | 1.37 | 8.9 | 3.4 | 9.5 | 214.1 | 212 | 133 | 116 | 33 | 82 | 226 | 7 | 0 | 0 | 2 | 14 | 7 | 3 | 4.14 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 81 | 32 | 32 | 10 | 10 | 4.57 | .322 | 1.39 | 8.5 | 4.0 | 9.0 | 187.0 | 177 | 113 | 95 | 21 | 83 | 188 | 0 | 0 | 0 | 0 | 13 | 6 | 8 | 3.88 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 32 | 32 | 8 | 16 | 5.57 | .337 | 1.52 | 10.3 | 3.3 | 5.4 | 216.1 | 248 | 147 | 134 | 26 | 80 | 129 | 7 | 0 | 0 | 1 | 10 | 2 | 4 | 4.51 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 29 | 29 | 8 | 12 | 5.58 | .341 | 1.54 | 9.2 | 4.6 | 6.6 | 182.1 | 187 | 124 | 113 | 26 | 94 | 133 | 3 | 0 | 0 | 0 | 11 | 2 | 2 | 4.98 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 85 | 0 | 8 | 4 | 3.81 | .315 | 1.35 | 7.6 | 4.6 | 8.8 | 113.1 | 95 | 54 | 48 | 10 | 58 | 110 | 0 | 5 | 2 | 0 | 0 | 3 | 0 | 3.82 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 69 | 0 | 3 | 5 | 2.93 | .284 | 1.17 | 7.1 | 3.6 | 9.5 | 70.2 | 55 | 26 | 23 | 6 | 28 | 74 | 0 | 5 | 2 | 0 | 0 | 1 | 0 | 3.24 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 69 | 0 | 1 | 4 | 2.72 | .297 | 1.27 | 7.5 | 4.0 | 8.3 | 49.2 | 41 | 16 | 15 | 7 | 22 | 45 | 0 | 9 | 4 | 0 | 0 | 0 | 5 | 4.37 |