| SP | Johnson, W.Johnson, Walter † >> | 26 | 1913 | R | 95 | 25 | 25 | 11 | 8 | 3.29 | .275 | 1.11 | 7.5 | 2.5 | 5.3 | 175.0 | 146 | 71 | 64 | 11 | 48 | 103 | 5 | 0 | 0 | 1 | 18 | 5 | 2 | 3.55 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 24 | 24 | 11 | 4 | 4.04 | .302 | 1.28 | 8.7 | 2.9 | 4.3 | 164.2 | 158 | 77 | 74 | 19 | 53 | 79 | 2 | 0 | 0 | 1 | 14 | 3 | 5 | 4.57 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 24 | 24 | 12 | 6 | 3.32 | .256 | 1.01 | 6.8 | 2.4 | 6.4 | 157.1 | 118 | 61 | 58 | 14 | 41 | 111 | 3 | 0 | 0 | 2 | 17 | 3 | 1 | 3.59 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 59 | 0 | 4 | 1 | 3.64 | .291 | 1.18 | 7.5 | 3.2 | 9.7 | 54.1 | 45 | 26 | 22 | 7 | 19 | 58 | 0 | 3 | 1 | 0 | 0 | 3 | 0 | 3.76 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 37 | 0 | 4 | 0 | 1.33 | .238 | 0.93 | 3.8 | 4.7 | 8.6 | 40.2 | 17 | 6 | 6 | 4 | 21 | 38 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 3.98 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 57 | 0 | 2 | 3 | 5.29 | .322 | 1.43 | 9.2 | 3.8 | 8.2 | 47.2 | 48 | 29 | 28 | 9 | 20 | 43 | 0 | 0 | 3 | 0 | 0 | 0 | 6 | 4.94 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 28 | 0 | 1 | 1 | 5.11 | .351 | 1.62 | 11.6 | 3.4 | 6.8 | 24.2 | 31 | 14 | 14 | 3 | 9 | 18 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.25 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 73 | 8 | 0 | 2 | 0 | 4.01 | .267 | 1.05 | 5.6 | 4.1 | 7.1 | 24.2 | 15 | 11 | 11 | 3 | 11 | 19 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.54 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 8 | 0 | 1 | 2 | 1.45 | .291 | 1.18 | 2.5 | 8.5 | 2.0 | 18.2 | 5 | 4 | 3 | 0 | 17 | 4 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.56 |