| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 89 | 24 | 24 | 13 | 6 | 2.66 | .261 | 1.05 | 7.1 | 2.4 | 5.3 | 179.1 | 142 | 59 | 53 | 13 | 47 | 105 | 8 | 0 | 0 | 4 | 18 | 1 | 2 | 3.58 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 24 | 24 | 13 | 6 | 3.67 | .298 | 1.28 | 7.3 | 4.1 | 5.2 | 152.0 | 124 | 67 | 62 | 12 | 70 | 88 | 1 | 0 | 0 | 0 | 14 | 0 | 2 | 4.25 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 66 | 23 | 22 | 7 | 9 | 3.56 | .293 | 1.22 | 8.3 | 2.7 | 5.3 | 144.0 | 133 | 60 | 57 | 17 | 43 | 84 | 3 | 0 | 0 | 0 | 14 | 3 | 3 | 4.33 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 58 | 0 | 5 | 3 | 2.96 | .266 | 1.09 | 5.7 | 4.1 | 8.5 | 70.0 | 44 | 28 | 23 | 4 | 32 | 66 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.23 |
| RP | Boxberger, B.Boxberger, Brad # >> | 26 | 2014 | R | 83 | 48 | 0 | 4 | 2 | 5.70 | .317 | 1.39 | 8.2 | 4.4 | 6.7 | 47.1 | 43 | 32 | 30 | 7 | 23 | 35 | 0 | 2 | 3 | 0 | 0 | 0 | 2 | 4.91 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 28 | 0 | 1 | 0 | 2.67 | .316 | 1.29 | 5.4 | 6.3 | 10.2 | 30.1 | 18 | 9 | 9 | 1 | 21 | 34 | 0 | 1 | 1 | 0 | 0 | 3 | 5 | 3.57 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 29 | 0 | 2 | 4 | 1.99 | .278 | 1.16 | 7.2 | 3.4 | 9.0 | 40.2 | 32 | 10 | 9 | 2 | 15 | 40 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 2.78 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 56 | 0 | 4 | 5 | 3.21 | .236 | 0.89 | 5.6 | 2.5 | 9.3 | 61.2 | 38 | 23 | 22 | 7 | 17 | 63 | 0 | 29 | 2 | 0 | 0 | 2 | 4 | 3.36 |