| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 34 | 34 | 9 | 14 | 4.61 | .307 | 1.30 | 7.7 | 4.0 | 7.1 | 169.2 | 145 | 94 | 87 | 20 | 76 | 133 | 1 | 0 | 0 | 0 | 14 | 5 | 3 | 4.40 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 34 | 34 | 8 | 12 | 3.79 | .288 | 1.18 | 8.3 | 2.3 | 4.9 | 197.1 | 182 | 94 | 83 | 24 | 51 | 107 | 1 | 0 | 0 | 0 | 17 | 6 | 6 | 4.37 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 32 | 32 | 7 | 10 | 4.26 | .269 | 1.08 | 7.4 | 2.3 | 8.7 | 190.1 | 156 | 93 | 90 | 30 | 49 | 184 | 3 | 0 | 0 | 2 | 14 | 5 | 6 | 3.97 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 32 | 32 | 14 | 7 | 3.73 | .301 | 1.27 | 6.9 | 4.6 | 3.8 | 195.1 | 149 | 85 | 81 | 18 | 100 | 83 | 1 | 0 | 0 | 1 | 19 | 3 | 3 | 4.93 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 83 | 0 | 11 | 3 | 2.57 | .256 | 1.01 | 6.3 | 2.9 | 9.4 | 108.2 | 75 | 31 | 31 | 8 | 35 | 113 | 0 | 2 | 1 | 0 | 0 | 2 | 7 | 2.90 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 76 | 0 | 7 | 5 | 2.27 | .270 | 1.08 | 5.5 | 4.3 | 8.7 | 99.0 | 60 | 28 | 25 | 5 | 47 | 96 | 0 | 3 | 3 | 0 | 0 | 3 | 0 | 3.23 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 50 | 0 | 4 | 2 | 2.55 | .300 | 1.27 | 8.0 | 3.5 | 5.3 | 60.0 | 53 | 21 | 17 | 7 | 23 | 35 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.55 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 37 | 0 | 1 | 2 | 3.00 | .254 | 1.00 | 6.0 | 3.0 | 8.6 | 45.0 | 30 | 15 | 15 | 8 | 15 | 43 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.47 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 33 | 29 | 0 | 3 | 2 | 2.57 | .239 | 0.91 | 6.4 | 1.8 | 5.9 | 35.0 | 25 | 12 | 10 | 2 | 7 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.11 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 20 | 0 | 1 | 0 | 3.48 | .279 | 1.11 | 6.8 | 3.6 | 8.1 | 20.2 | 15 | 8 | 8 | 3 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.50 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 21 | 0 | 5 | 1 | 4.17 | .318 | 1.39 | 7.6 | 5.0 | 6.3 | 112.1 | 94 | 53 | 52 | 10 | 62 | 78 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 4.46 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 67 | 0 | 3 | 8 | 3.33 | .296 | 1.22 | 7.3 | 3.7 | 7.3 | 73.0 | 59 | 29 | 27 | 8 | 30 | 59 | 0 | 34 | 7 | 0 | 0 | 3 | 3 | 4.16 |