| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 29 | 29 | 5 | 14 | 3.84 | .299 | 1.26 | 7.4 | 3.9 | 8.2 | 199.0 | 164 | 91 | 85 | 15 | 86 | 182 | 7 | 0 | 0 | 0 | 16 | 5 | 5 | 3.52 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 29 | 29 | 14 | 8 | 3.86 | .282 | 1.16 | 8.5 | 1.9 | 5.8 | 181.2 | 171 | 81 | 78 | 12 | 39 | 116 | 5 | 0 | 0 | 3 | 16 | 4 | 2 | 3.29 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 26 | 26 | 13 | 8 | 4.21 | .333 | 1.49 | 10.2 | 3.2 | 4.5 | 169.0 | 191 | 94 | 79 | 23 | 61 | 85 | 2 | 0 | 0 | 1 | 14 | 1 | 2 | 4.86 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 69 | 0 | 7 | 1 | 3.59 | .313 | 1.34 | 7.5 | 4.6 | 9.2 | 80.1 | 67 | 33 | 32 | 8 | 41 | 82 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 3.86 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 51 | 0 | 5 | 1 | 4.94 | .308 | 1.33 | 6.9 | 5.1 | 9.0 | 51.0 | 39 | 28 | 28 | 6 | 29 | 51 | 0 | 1 | 0 | 0 | 0 | 0 | 6 | 4.24 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 30 | 0 | 3 | 3 | 4.25 | .294 | 1.25 | 9.0 | 2.3 | 6.8 | 36.0 | 36 | 17 | 17 | 6 | 9 | 27 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 4.42 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 38 | 0 | 1 | 2 | 6.51 | .341 | 1.53 | 8.8 | 5.1 | 7.8 | 37.1 | 36 | 31 | 27 | 7 | 21 | 32 | 0 | 0 | 7 | 0 | 0 | 1 | 0 | 5.51 |
| CL | Kimbrel, C.Kimbrel, Craig † $ >> | 24 | 2012 | R | 100 | 46 | 0 | 1 | 2 | 3.35 | .271 | 1.07 | 6.5 | 3.1 | 9.4 | 43.0 | 31 | 16 | 16 | 3 | 15 | 45 | 0 | 35 | 3 | 0 | 0 | 2 | 3 | 3.00 |