| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 98 | 29 | 29 | 14 | 9 | 3.84 | .283 | 1.17 | 8.2 | 2.4 | 8.8 | 197.0 | 179 | 94 | 84 | 25 | 52 | 192 | 8 | 0 | 0 | 1 | 16 | 2 | 4 | 3.52 |
| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 92 | 28 | 28 | 10 | 10 | 4.67 | .325 | 1.42 | 9.0 | 3.8 | 5.8 | 185.0 | 185 | 101 | 96 | 34 | 78 | 119 | 1 | 0 | 0 | 0 | 13 | 4 | 1 | 5.43 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 27 | 27 | 11 | 10 | 4.64 | .316 | 1.36 | 9.4 | 2.8 | 8.6 | 155.1 | 162 | 90 | 80 | 26 | 49 | 148 | 0 | 0 | 0 | 0 | 14 | 4 | 1 | 4.30 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 77 | 27 | 26 | 9 | 13 | 6.09 | .353 | 1.61 | 10.4 | 4.2 | 5.5 | 146.1 | 168 | 109 | 99 | 18 | 68 | 89 | 2 | 0 | 0 | 0 | 10 | 3 | 5 | 4.84 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 66 | 0 | 2 | 4 | 4.71 | .349 | 1.58 | 10.2 | 4.2 | 7.8 | 78.1 | 88 | 46 | 41 | 8 | 36 | 68 | 0 | 0 | 3 | 0 | 0 | 2 | 1 | 4.05 |
| RP | Treinen, B.Treinen, Blake # >> | 30 | 2018 | R | 78 | 53 | 0 | 3 | 4 | 4.58 | .324 | 1.44 | 8.8 | 4.1 | 6.2 | 55.0 | 54 | 28 | 28 | 10 | 25 | 38 | 0 | 0 | 4 | 0 | 0 | 0 | 1 | 5.35 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 33 | 0 | 3 | 0 | 3.52 | .324 | 1.41 | 6.6 | 6.2 | 9.9 | 38.1 | 28 | 15 | 15 | 3 | 26 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.95 |
| SU | Davis, W.Davis, Wade # >> | 29 | 2015 | R | 89 | 52 | 0 | 1 | 3 | 3.64 | .262 | 1.07 | 6.7 | 3.0 | 9.2 | 54.1 | 40 | 23 | 22 | 8 | 18 | 55 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 3.89 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 51 | 0 | 2 | 2 | 1.88 | .240 | 0.91 | 5.0 | 3.3 | 11.4 | 52.2 | 29 | 11 | 11 | 5 | 19 | 66 | 0 | 38 | 3 | 0 | 0 | 2 | 1 | 2.92 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 27 | 0 | 4 | 2 | 4.91 | .325 | 1.43 | 9.8 | 3.2 | 5.0 | 113.2 | 123 | 71 | 62 | 12 | 40 | 63 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.35 |