| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 21 | 21 | 8 | 10 | 3.92 | .292 | 1.23 | 8.6 | 2.5 | 4.6 | 153.2 | 146 | 67 | 67 | 14 | 43 | 78 | 7 | 0 | 0 | 1 | 12 | 1 | 2 | 4.03 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 19 | 19 | 7 | 5 | 4.55 | .311 | 1.35 | 9.7 | 2.5 | 5.0 | 128.2 | 138 | 68 | 65 | 11 | 36 | 71 | 3 | 0 | 0 | 0 | 8 | 0 | 2 | 3.85 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 50 | 0 | 6 | 1 | 1.67 | .234 | 0.91 | 5.7 | 2.5 | 8.8 | 86.0 | 54 | 20 | 16 | 5 | 24 | 84 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 2.67 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 39 | 0 | 3 | 1 | 1.69 | .256 | 1.03 | 5.6 | 3.7 | 7.0 | 53.1 | 33 | 12 | 10 | 4 | 22 | 41 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3.68 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 36 | 0 | 2 | 1 | 4.60 | .305 | 1.30 | 8.4 | 3.3 | 6.7 | 47.0 | 44 | 24 | 24 | 6 | 17 | 35 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 4.32 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 27 | 0 | 3 | 0 | 4.05 | .292 | 1.24 | 6.6 | 4.8 | 9.0 | 26.2 | 19 | 12 | 12 | 3 | 14 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.12 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 5 | 0 | 1 | 0 | 5.68 | .387 | 1.89 | 16.5 | 1.5 | 7.5 | 6.1 | 11 | 4 | 4 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.83 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 18 | 0 | 1 | 3 | 3.40 | .278 | 1.16 | 7.5 | 3.0 | 9.2 | 42.1 | 35 | 17 | 16 | 4 | 14 | 43 | 0 | 4 | 2 | 0 | 0 | 0 | 1 | 3.19 |